New Descriptor for Glomerulus Detection in Kidney Microscopy Image
Glomerulus detection is a key step in histopathological evaluation of microscopy images of kidneys. However, the task of automatic detection of glomeruli poses challenges due to the disparity in sizes and shapes of glomeruli in renal sections. Moreover, extensive variations of their intensities due to heterogeneity in immunohistochemistry staining are ...
Tsuyoshi Kato +5 more
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Revealing VCAN as a Potential Common Diagnostic Biomarker of Renal Tubules and Glomerulus in Diabetic Kidney Disease Based on Machine Learning, Single-Cell Transcriptome Analysis and Mendelian Randomization [PDF]
Background Diabetic kidney disease (DKD) is recognized as a significant complication of diabetes mellitus and categorized into glomerular DKDs and tubular DKDs, each governed by distinct pathological mechanisms and biomarkers.
Li Jiang, Jie Jian, Xulin Sai, Xiai Wu
doaj +1 more source
Paired and altruistic kidney donation in the UK: algorithms and experimentation [PDF]
We study the computational problem of identifying optimal sets of kidney exchanges in the UK. We show how to expand an integer programming-based formulation [1, 19] in order to model the criteria that constitute the UK definition of optimality.
David F. Manlove +3 more
core +1 more source
Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants
Background: During normal human kidney development, nephrogenesis (the formation of nephrons) is complete by term birth, with the majority of nephrons formed late in gestation.
Danica Ryan +10 more
doaj +1 more source
Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus
Thyroglobulin (Tg) is an essential substrate for thyroid hormone biosynthesis whose production is primarily limited to the thyroid follicular cell. We have previously identified an approximately 1.2 kb fragment of Tg mRNA in cultured mouse mesangial cells, and in the present study provide evidence showing that this transcript is transcribed and ...
Huhehasi, Wu +14 more
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The RIFLE (risk, injury, failure, loss, and end-stage) classification is widely used to gauge the severity of acute kidney injury, but its efficacy has not been formally tested in geriatric patients.
Chao, Chia-Ter;Wu, Vin-Cent;Lai, Chun-Fu;Shiao, Chih-Chung;Huang, Tao-Min;Wu, Pei-Chen;Tsai, I-Jung;Hou, Chun-Cheng;Wang, Wei-Jie;Tsai, Hung-Bin;Lin, Yu-Feng;Chiang, Wen-Chih;Lin, Shuei-Liong;Tsai, Pi-Ru;Ko, Wen-Je;Wu, Ming-Shiou;Wu, Kuan-Dun +1 more
core +1 more source
Anatomical and Histological Study of Shark (Carcharhinus sorrah) Kidney
Sharks are sea water fishes belong to the class Chondrichthyes, Subclass Elasmobranchii. Sharks are cartilaginous fish that have a different osmoregulation process than any other sea water fish. Cartilaginous fish is the only vertebrate that can maintain
Hikmah Supriyati +2 more
doaj +1 more source
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies [PDF]
Chronic kidney disease (CKD) affects -10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function
Cechova, Sylvia +52 more
core +2 more sources
Structural Alterations of the Glomerular Wall And Vessels in Early Stages of Diabetes Mellitus: Light and Transmission Electron Microscopic Study [PDF]
Objective: The capillary changes at the initial stage of diabetes may show an angioarchitecture clearly different from those of later stages and,/or very severe glomerular change. However, the onset of alterations in the early phases is unclear.
Dkhil MA, Awadallah RS, Danfour MA
doaj
AbstrakHiperglikemia menjadi ancaman serius karena berdampak buruk terhadap keluaran klinis karena dapat menyebabkan gangguan fungsi imun serta lebih rentan terkena infeksi, perburukan sistem kardiovaskuler, trombosis, peningkatan inflamasi, disfungsi ...
Melati Setia Ningsih +2 more
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