Results 71 to 80 of about 1,182,937 (319)

Biomarker Acute Kidney Injury (AKI) pada Sepsis

Jurnal Kesehatan Andalas, 2018
Sepsis didefinisikan sebagai infeksi bersama dengan manifestasi sistemik dari infeksi. Sepsis berat adalah penyebab 50% kasus acute kidney injury (AKI) pada pasien kritis.
Dional Setiawan, Harnavi Harun, Syaiful Azmi, Drajad Priyono   +3 more
doaj   +1 more source

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]

, 2011
Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core   +1 more source

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Potential of karamunting (Rhodomyrtus tomentosa) fraction against kidney damage in diabetic rats

Herba Polonica, 2021
Introduction: Karamunting (Rhodomyrtus tomentosa) is Indonesian native plant that contains high anti-oxidant compounds with the potential to suppress oxidative stress activity in cells. This study is the first research to specifically explore the role of
Saleh Mgs Irsan, Hidayat Rachmat, Febriyanto Geri, Parisa Nita   +3 more
doaj   +1 more source

Clinical, histological, and serological predictors of renal function loss in lupus nephritis.

Arthritis Care &Research, Accepted Article.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M Guthridge, Carla Guthridge, Peter Izmirly, Jill P Buyon, H.Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership RA/SLE Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Hubungan antara Lama Menjalani Terapi Hemodialisis dengan Kualitas Hidup pada Pasien Chronic Kidney Disease di RS M. Djamil Padang

Jurnal Ilmu Kesehatan Indonesia
Latar Belakang: Penyakit chronic kidney disease (CKD) merupakan abnormalitas struktur dan fungsi ginjal dengan atau tanpa penurunan laju filtrasi glomerulus (LFG) atau kadar glomerulus kurang dari 60 mL/menit/1,73m2 yang bersifat ireversibel.
Hanifah Nabilah, Rudy Afriant, Yaslinda Yaunin, Irza Wahid, Eldi Sauma   +4 more
doaj   +1 more source

Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including α-actinin 4

Clinical Proteomics, 2011
Purpose The objective of the present study is to identify proteins that change in the extent of the modification with O-linked N-acetylglucosamine (O-GlcNAcylation) in the kidney from diabetic model Goto-Kakizaki (GK) rats, and to discuss the relation ...
Akimoto Yoshihiro, Miura Yuri, Toda Tosifusa, Wolfert Margreet A, Wells Lance, Boons Geert-Jan, Hart Gerald W, Endo Tamao, Kawakami Hayato   +8 more
doaj   +1 more source

Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys [PDF]

Journal of Extracellular Vesicles, 2016
Non-invasive tests to identify age and early disease-associated pathology within the kidney are needed. Specific populations of urinary extracellular vesicles (EVs) could potentially be used for such a diagnostic test.
Anne E. Turco, Wing Lam, Andrew D. Rule, Aleksandar Denic, John C. Lieske, Virginia M. Miller, Joseph J. Larson, Walter K. Kremers, Muthuvel Jayachandran   +8 more
doaj   +1 more source