Recent advances in the modelling of renal function [PDF]
Differential equation models have become an indispensable tool in the effort towards a complete understanding of hypertonic urine formation. Recent advances in this field include the treatment of a kidney model as an inverse prob lern, the modelling of ...
Lory, Peter
core
Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova +21 more
wiley +1 more source
Significance of suPAR in glomerular diseases
The soluble urokinase-type plasminogen activator receptor(suPAR) is a new type of biomarkers, and can be used for a variety of diagnosis, evaluation and prognosis of many diseases.
RUAN Dong-dong, YUAN Jun
doaj
Immune Cell Infiltrate in Chronic-Active Antibody-Mediated Rejection
Background: Little is known about immune cell infiltrate type in the kidney allograft of patients with chronic-active antibody-mediated rejection (c-aABMR).Methods: In this study, multiplex immunofluorescent staining was performed on 20 cases of biopsy ...
Kasia A. Sablik +4 more
doaj +1 more source
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro [PDF]
PKD2 is mutated in 15% of patients with autosomal dominant polycystic kidney disease (ADPKD). Polycystin-2 (PC2), the PKD2 protein, is a nonselective Ca2 + -permeable cation channel which may function at the cell surface and ER. Nevertheless, the factors
Kane, M.E. +4 more
core +2 more sources
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
AbstrakAnemia merupakan salah satu masalah utama pada pasien penyakit ginjal kronik. Tinggi rendahnya laju filtrasi glomerulus mempengaruhi kejadian anemia pada penyakit ginjal kronik.
Rahmat Hidayat +2 more
doaj
Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection [PDF]
Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have
Brown RD +7 more
core +3 more sources
Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez +8 more
wiley +1 more source
Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee +7 more
wiley +1 more source

