Results 81 to 90 of about 576,914 (292)

Immune Cell Infiltrate in Chronic-Active Antibody-Mediated Rejection

open access: yesFrontiers in Immunology, 2020
Background: Little is known about immune cell infiltrate type in the kidney allograft of patients with chronic-active antibody-mediated rejection (c-aABMR).Methods: In this study, multiplex immunofluorescent staining was performed on 20 cases of biopsy ...
Kasia A. Sablik   +4 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Glomerulus-specific, long-latency activity in the olfactory bulb granule cell network.

open access: yes, 2018
Reliable, stimulus-specific temporal patterns of action potentials have been proposed to encode information in many brain areas, perhaps most notably in the olfactory system.
Vikrant Kapoor (5062802)   +1 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

Morphological Description and Histological Structure of Kidney in Barn Owl Tyto alba

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
  The morphological description and histological structure of Kidney in barn owl Tyto alba have been invesigated. The results of present study revealed that barn owl has pair of elongated solid kidney situated symmetrically on both sides of vertebral ...
Isrra A. A. Khadhim, Hussain A. Dauod
doaj  

New Descriptor for Glomerulus Detection in Kidney Microscopy Image

open access: yesCoRR, 2015
Glomerulus detection is a key step in histopathological evaluation of microscopy images of kidneys. However, the task of automatic detection of glomeruli poses challenges due to the disparity in sizes and shapes of glomeruli in renal sections. Moreover, extensive variations of their intensities due to heterogeneity in immunohistochemistry staining are ...
Tsuyoshi Kato   +5 more
openaire   +2 more sources

Guía del protocolo para Glomerulus Chip de S Musah, et al. (2018)

open access: yes, 2021
(EN) The Figures were developed with Biorender.com and its aim is to provide a detailed visual guide to a protocol described in S. Musah, N. Dimitrakakis, DM Camacho, GM Church, and DE Ingber, “Directed differentiation of human induced pluripotent stem ...
García, María Belem, Chapa, Christian
core   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Histological changes in kidney.

open access: yes
Light micrographs of a paraffin section stained with eosin (40x). a; kidney in -ve T0, b; kidney in +ve T0, c; kidney in T1, d; kidney in T2, e; kidney in T3, f; kidney in T4, g; kidney in T5, h; kidney in T6, I; kidney in T7.
Qandeel Minahal (17873640)   +4 more
core   +1 more source

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