Results 101 to 110 of about 576,914 (292)

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

Ekstrak Etanol Daun Alpukat (Persea americana Mill.) sebagai Penurun Edema Glomerulus dan Kerusakan Sel Ginjal Tikus Putih (Rattus norvegicus) [PDF]

open access: yes, 2018
Avocado leaves (Persea americana Mill.) historically used as a herbal medicine used to ease the expense of urine and crushed a kidney stone in the urinary tract. Avocado leaves contain sugar, d-parseit, quercetin, flavonoids, and compounds sterin. The
WALUYO, Joko   +2 more
core   +1 more source

Anatomical and Histological Study of Shark (Carcharhinus sorrah) Kidney

open access: yesBiology, Medicine & Natural Product Chemistry, 2019
Sharks are sea water fishes belong to the class Chondrichthyes, Subclass Elasmobranchii. Sharks are cartilaginous fish that have a different osmoregulation process than any other sea water fish. Cartilaginous fish is the only vertebrate that can maintain
Hikmah Supriyati   +2 more
doaj   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

open access: yesAdvanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang   +13 more
wiley   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao   +7 more
wiley   +1 more source

Histological changes in muscles and kidney.

open access: yes
Light micrographs of a paraffin section stained with eosin (40x). a; muscles in -ve P0, b; muscles in P1, c; muscles in P2, d; muscles in P3, e; muscles in +veP0, f; kidney in -ve P0, g; kidney in P1, h; kidney in P2, i; kidney in P3, j; kidney in +ve P0.
Zakia Kanwal (6595427)   +6 more
core   +1 more source

Towards a Glomerulus Nanoscale Spatial Atlas [PDF]

open access: yes, 2022
Thesis (Master's)--University of Washington, 2022The glomerulus is the basic filtration apparatus of the kidney, where thousands of the capillary-rich structures function to remove waste products from the blood stream while retaining macromolecules and ...
Ali, Adilijiang
core  

Checkpoint‐Directed Glycoengineering Reprograms the Vascular Lumen for Siglec‐Mediated Immune Regulation

open access: yesAdvanced Science, EarlyView.
Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana   +19 more
wiley   +1 more source

Analysis of kidney glomerular and microvascular transcriptomes

open access: yes, 2007
Kidney glomeruli play a crucial role in the maintenance of body homeostasis. Many diseases attack the kidney function by primarily affecting glomeruli.
Liqun He (212666)
core   +1 more source

Structural Alterations of the Glomerular Wall And Vessels in Early Stages of Diabetes Mellitus: Light and Transmission Electron Microscopic Study [PDF]

open access: yesLibyan Journal of Medicine, 2007
Objective: The capillary changes at the initial stage of diabetes may show an angioarchitecture clearly different from those of later stages and,/or very severe glomerular change. However, the onset of alterations in the early phases is unclear.
Dkhil MA, Awadallah RS, Danfour MA
doaj  

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