Results 91 to 100 of about 127,828 (193)

Optimized reconstruction of the absorption spectra of kidney tissues from the spectra of tissue components using the least squares method

open access: yesJournal of Biophotonics, EarlyView.
The absorption coefficient spectra of healthy and cancerous kidney tissues were reconstructed from the absorption spectra of tissue components using constant weights. Both reconstructions allowed to calculate the concentrations of the tissue components and a comparison between the healthy and chromophobe renal cell carcinoma kidney showed an increase ...
Maria R. Pinheiro   +7 more
wiley   +1 more source

Multilocular Cystic Nephroma – A Surgical and Radiological Dilemma [PDF]

open access: yes, 2011
Multilocular cystic nephroma is a slow growing benign renal tumor. It has been identified as exclusive adult lesion, more common in females. It commonly occurs as an asymtomatic mass, occasionally with hematuria.
Anil Malleshi Betigeri , Boopathi subramaniyam, Int J Cur Bio Med Sci.
core  

A Physiologically Based Modeling Approach to Evaluate Intravenous Levetiracetam Dosing in Term and Preterm Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Seizures are the most common neurologic emergency in neonates and are associated with significant morbidity and mortality. Current first‐line pharmacotherapy, phenobarbital, is associated with serious adverse effects, including impairment of the developing brain.
Alexis Johnson   +4 more
wiley   +1 more source

The effect of elexacaftor–tezacaftor–ivacaftor on liver stiffness in children with cystic fibrosis

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Cystic fibrosis hepato‐biliary involvement (CFHBI) is a common comorbidity in patients with CF and is associated with increased morbidity and mortality. The effect of the new and highly potent CF transmembrane conductance regulator modulator therapy, elexacaftor–tezacaftor–ivacaftor (ETI), on CFHBI, is still unclear.
Stefanie Diemer   +4 more
wiley   +1 more source

Wilms Tumor in Children with AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 10–15% of children with Wilms tumor (WT) have predisposing genetic syndromes. Somatic mutations are frequently identified; however, germline pathogenic variants in AMER1 are much less prevalent and are associated with osteopathia striata with cranial sclerosis (OSCS).
Insiyah Campwala   +9 more
wiley   +1 more source

Elevated Bromide Levels due to Tazemetostat Therapy Treated With Salt and Water Supplementation in Two Children With Atypical Teratoid Rhabdoid Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Atypical teratoid rhabdoid tumor (ATRT) is an embryonal CNS tumor that afflicts young children. The molecular process associated with ATRT is loss of SMARCB1 or SMARCA4, which causes EZH2 overactivation. Tazemetostat hydrobromide is an EZH2 inhibitor, which has shown efficacy in the treatment of ATRT. Tazemetostat is produced as a bromide salt
Thomas J. Galletta   +5 more
wiley   +1 more source

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo   +2 more
wiley   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes   +9 more
wiley   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An   +22 more
wiley   +1 more source

Sex-specific Expression of Estradiol Derivatives, Hydropersulfides and Ether Lipids Regulates Ferroptosis Sensitivity of Kidney Tubules

open access: yes, 2023
Linkermann A   +29 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy