Results 211 to 220 of about 139,844 (303)

Construction of a prognostic assessment model for diabetic nephropathy based on serum fibrinogen and renal tissue IFTA score

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the association between serum fibrinogen (FIB) and clinicopathological features and renal prognosis in type 2 diabetic nephropathy (T2DN), and develop a web‐based dynamic model to predict renal progression. Methods This paper retrospectively enrolled 173 biopsy‐proven T2DN patients and stratified them by the optimal FIB ...
Lin Ning, Xiaohong Zhang, Yuan Fang, Mengjie Weng, Yongjie Zhuo, Jianxin Wan   +5 more
wiley   +1 more source

Alporting Trouble Down the Tubules. [PDF]

Kidney Int Rep
Chan M, Gross O.
europepmc   +1 more source

Retrospective comparison of the clinical effects of oral semaglutide and SGLT2 inhibitors treatment in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This retrospective study compared oral semaglutide and SGLT2 inhibitors in patients with type 2 diabetes over 6 months. Both treatments significantly reduced HbA1c, body weight, and fat mass. Although the reduction in fat mass was comparable, changes in skeletal muscle mass tended to be less favorable with SGLT2 inhibitors than with oral semaglutide ...
Yasuhiro Omori, Ryota Usui, Yuji Yamazaki, Hitoshi Kuwata, Yoshiyuki Hamamoto, Yuichiro Yamada, Yutaka Seino   +6 more
wiley   +1 more source

In vivo expression of VCAM1 precedes nephron loss following kidney tubular necrosis. [PDF]

Sci Adv
Kristensen AM, Bordoni L, Nielsen MB, Faivre A, Kidmose H, Sardella D, Shipman KE, Krogstrup NV, Størling J, Birn H, Enger R, Schiessl IM.   +11 more
europepmc   +1 more source

Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic retinopathy (DR) is a prevalent chronic complication of type 2 diabetes mellitus (T2DM), contributing significantly to vision impairment. Circular RNAs (circRNAs) have emerged as key regulators in the pathogenesis of DR.
Wencheng An, Bingyan Wang, Fang Chen, Bo An, Shujing Zhou, Lin Jiang, Zhijun Cui, Xiaohong Ou, Wei Huang, Huixian Yan   +9 more
wiley   +1 more source

A comparative histochemical developmental study of the kidney and ureter in golden hamster (<i>Mesocricetus auratus</i>). [PDF]

Open Vet J
Ghazal KM, Al-Alwany EAH.
europepmc   +1 more source

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

Journal of Diabetes Investigation, EarlyView.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo, Fengjiao Zhang, Yu Jin, Menglu Zhu, Zhiqiang Kang   +4 more
wiley   +1 more source

Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease. [PDF]

Sci Adv
Rogg M, Weißer L, Maier JI, Sigle A, Helmstädter M, Stigler M, Sammarco A, Gräwe K, Andreev G, Kark C, Ramakrishnan SK, Özel C, Butt L, Arnold F, Bechtel-Walz W, Schilling O, Tanriver Y, Brinkkötter P, Grabbert M, Simons M, Werner M, Kretz O, Benzing T, Huber TB, Schell C.   +24 more
europepmc   +1 more source

Growth‐regulating proteins differ between British seawater fish species, shedding light on their ecological adaptations

Journal of Fish Biology, EarlyView.
Abstract Wnt proteins are a family of molecules that help control how cells grow, develop and communicate – processes that are fundamental to the development and health of all animals. Although Wnt pathways have been studied extensively in model species, very little is known about how they operate in marine fish.
Angeliki Maravelia, Soniya Malik, Clare Murcott, Ioannis Batzakas, Paraskevi Goggolidou   +4 more
wiley   +1 more source

Alport Syndrome is a Partial Tubulointerstitial Disease of the Kidney. [PDF]

Kidney Int Rep
Loderbauer L, Knaup KX, Reisenbüchler D, Kaiser N, Naas S, Schneider K, Wopperer FJ, Wiesener A, Pasutto F, Schiffer M, Daniel C, Broeker KAE, Merhof D, Buettner-Herold M, Wiesener MS.   +14 more
europepmc   +1 more source