Results 21 to 30 of about 134,704 (353)

Inhalation of mercury vapor can cause the toxic effects on rat kidney [PDF]

open access: yes, 2016
Dental amalgam has been used in dentistry as a filling material. The filler comprises mercury (Hg). It is considered one of the most important and widespread environmental pollutants, which poses a serious potential threat for the humans and animals ...
Akgul, Hayati Murat   +5 more
core   +1 more source

The Kidney and Uremic Toxin Removal: Glomerulus or Tubule? [PDF]

open access: yesSeminars in Nephrology, 2014
Chronic kidney disease (CKD) is a condition that affects approximately 10% of the adult population in developed countries. In patients with CKD adequate renal clearance is compromised, resulting in the accumulation of a plethora of uremic solutes.
Masereeuw, R.   +9 more
openaire   +4 more sources

Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]

open access: yes, 2017
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R.   +9 more
core   +2 more sources

Centrosome amplification disrupts renal development and causes cystogenesis [PDF]

open access: yes, 2018
International ...
Amanda Knoten   +79 more
core   +5 more sources

MORPHOLOGICAL AND HISTOLOGICAL STUDY FOR THE KIDNEYS OF COOT BIRD ( Fulica atra ) [PDF]

open access: yesBasrah Journal of Veterinary Research, 2012
Present study were carried out on ten adult males of coot bird, for determinate the histological structure of kidneys. The results were showed that each kidney consisted of three parts, a large cranial (mean of its length 28±0.15mm and its width13±0.08mm)
Abbas Lafi Batah
doaj   +1 more source

A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adulthood ...
Sarah Myram   +12 more
doaj   +1 more source

Endothelin-1 Drives Epithelial-Mesenchymal Transition In Hypertensive Nephroangiosclerosis [PDF]

open access: yes, 2016
BACKGROUND: Tubulointerstitial fibrosis, the final outcome of most kidney diseases, involves activation of epithelial mesenchymal transition (EMT). Endothelin‐1 (ET‐1) activates EMT in cancer cells, but it is not known whether it drives EMT in the kidney.
Belloni, Anna S   +13 more
core   +1 more source

Adult Mouse Kidney Stem Cells Orchestrate the De Novo Assembly of a Nephron via Sirt2‐Modulated Canonical Wnt/β‐Catenin Signaling

open access: yesAdvanced Science, 2022
Generation of kidney organoids using autologous kidney stem cells represents an attractive strategy for treating and potentially replacing the failing kidneys. However, whether adult mammalian kidney stem cells have regenerative capacity remains unknown.
Xiaobin Han, Zhongjie Sun
doaj   +1 more source

mutation: a benign genetic cause of proteinuria? [PDF]

open access: yesChildhood Kidney Diseases, 2023
Proteinuria is an important risk factor for renal and cardiovascular disease. It is associated with a risk for glomerulonephritis, chronic kidney disease, and end-stage renal disease.
Hyun Kyung Lee
doaj   +1 more source

Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]

open access: yes, 2009
Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Jones, E. A., Naylor, Richard William
core   +1 more source

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