Results 31 to 40 of about 134,704 (353)

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2 [PDF]

open access: yes, 1999
Deficiency of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) in humans leads to the syndrome of apparent mineralocorticoid excess (SAME), in which cortisol illicitly occupies mineralocorticoid receptors, causing sodium retention, hypokalemia, and ...
Arriza   +39 more
core   +3 more sources

Study the Anatomical Descriptions and Histological Observations of the Kidney in Golden Eagles (Aquila Chrysaetos)

open access: yesThe Iraqi Journal of Veterinary Medicine, 2012
The present study is preliminary investigate of the kidney gross morphology and some histological observations was studied in golden eagle (Aquila Chrysaetus).
Ramzi Abdul ghafoor Abood AL-Agele
doaj   +1 more source

An immunohistochemical study of the diagnostic value of TREM-1 as marker for fatal sepsis cases [PDF]

open access: yes, 2019
Triggering receptor expressed on myeloid cells-1 (TREM-1) is produced and up-regulated by exposure of myeloid cells to lipopolysaccharides or other components of either bacterial or fungal origin, which causes it to be strongly expressed on phagocytes ...
Bolino, G.   +4 more
core   +1 more source

A biomimetic kidney tubule model

open access: yes, 2020
A critical barrier in the nephrology field is the lack of appropriate in vitro renal tubule models that allow manipulation of various mechanical factors, facilitating studies of disease pathophysiology and drug discovery. Here we report development of a novel in vitro assay system comprised of a renal tubule within an elasto-plastic extracellular ...
Mehes, Elod   +5 more
openaire   +2 more sources

TNF-α induces Claudin-1 expression in renal tubules in Alport mice

open access: yesPLoS ONE, 2022
Claudin-1 (CL-1) is responsible for the paracellular barrier function of glomerular parietal epithelial cells (PEC) in kidneys, but the role of CL-1 in proximal tubules remains to be elucidated.
Manami Iida   +7 more
doaj   +2 more sources

Tubulopathy: the clinical and genetic approach in diagnosis [PDF]

open access: yesChildhood Kidney Diseases, 2023
Remarkable advances in genetic diagnosis expanded our knowledge about inherited tubulopathies and other genetic kidney diseases. This review suggests a simple categorization of inherited tubular disease, clarifies the concept of autosomal dominant ...
Jinwoon Joung, Heeyeon Cho
doaj   +1 more source

Cell volume regulation in the proximal tubule of rat kidney proximal tubule cell volume regulation [PDF]

open access: yes, 2017
We developed a dynamic model of a rat proximal convoluted tubule cell in order to investigate cell volume regulation mechanisms in this nephron segment.
Edwards, Aurelie, Layton, Anita T.
core   +1 more source

Disturbances in Switching between Canonical and Non-Canonical Wnt Signaling Characterize Developing and Postnatal Kidneys of Dab1−/− (yotari) Mice

open access: yesBiomedicines, 2023
This study aims to determine the protein expression patterns of acetylated α-tubulin, inversin, dishevelled-1, Wnt5a/b, and β-catenin in developing (E13.5 and E15.5) and early postnatal (P4 and P14) kidneys of Dab1−/− (yotari) mice, their role in ...
Ilija Perutina   +8 more
doaj   +1 more source

Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

open access: yes, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola   +3 more
core   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

open access: yes, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica   +8 more
core   +2 more sources

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