Results 71 to 80 of about 134,704 (353)

Kidney regeneration: common themes from the embryo to the adult [PDF]

, 2013
The vertebrate kidney has an inherent ability to regenerate following acute damage. Successful regeneration of the injured kidney requires the rapid replacement of damaged tubular epithelial cells and reconstitution of normal tubular function ...
Cirio, Maria Cecilia, Davidson, Alan J., de Caestecker, Mark P., de Groh, Eric D., Hukriede, Neil A.   +4 more
core   +1 more source

The proximal tubule in the pathophysiology of the diabetic kidney

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2011
Diabetic nephropathy is a leading cause of end-stage renal disease. A better understanding of the molecular mechanism involved in the early changes of the diabetic kidney may permit the development of new strategies to prevent diabetic nephropathy. This review focuses on the proximal tubule in the early diabetic kidney, particularly on its exposure and
openaire   +4 more sources

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Deep-learning model for evaluating histopathology of acute renal tubular injury

Scientific Reports
Tubular injury is the most common cause of acute kidney injury. Histopathological diagnosis may help distinguish between the different types of acute kidney injury and aid in treatment.
Thi Thuy Uyen Nguyen, Anh-Tien Nguyen, Hyeongwan Kim, Yu Jin Jung, Woong Park, Kyoung Min Kim, Ilwoo Park, Won Kim   +7 more
doaj   +1 more source

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane [PDF]

, 2012
Despite being engineered to avoid renal clearance, many cationic polymer (polycation)-based siRNA nanoparticles that are used for systemic delivery are rapidly eliminated from the circulation.
Andrews, Bartlett, Bartlett, Bennett, Burke, C. H. J. Choi, Castanotto, Davis, Davis, de Fougerolles, de Wolf, Foglieni, Gao, H. Han, J. E. Zuckerman, Kanwar, Kanwar, Lahdenkari, M. E. Davis, Malek, Merkel, Merkel, Mishra, Ogawa, Oney, Soo Choi, Takemoto   +26 more
core   +3 more sources

Photocrosslinkable Kidney Decellularized Extracellular Matrix‐Based Bioink for 3D Bioprinting

Advanced Healthcare Materials, EarlyView.
A photocrosslinkable bioink is developed from methacrylated decellularized porcine kidney extracellular matrix to create kidney‐specific 3D constructs. This bioink supports high cell viability, promotes multicellular spheroid formation, and enables stable multilayer bioprinting with tunable mechanical properties, providing a versatile platform for ...
Jaemyung Shin, Nima Tabatabaei Rezaei, Subin Choi, Zhangkang Li, Deok‐Ho Kim, Keekyoung Kim   +5 more
wiley   +1 more source

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]

, 2016
We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe, Azzato, Francisco, Cao, Gabriel Fernando, Gómez Llambí de Oromí, Hernán Jorge, Milei, Jose, Muller, Maria Angelica, Otero-Losada, Matilde Estela, Ottaviano, Graciela Mabel   +7 more
core   +1 more source

The first decade of Kidney International: treasure hunt for the kidney tubule

Kidney International, 2020
This article is part of the KI 60th anniversary series. This month’s topic is related to seminal contributions related to various tubular segments in the normal and diseased kidney.
openaire   +4 more sources

3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration

Advanced Healthcare Materials, EarlyView.
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano, Mohamed Ali, James J. Yoo, Sang Jin Lee, Anthony Atala   +4 more
wiley   +1 more source

Anterior Kidney of the Yellow Mystus, Hemibagrus filamentus (Fang and Chaux, 1949)

Walailak Journal of Science and Technology, 2013
There is no available report on histological observation of the anterior kidney of the yellow mystus Hemibagrus filamentus (Fang and Chaux, 1949). Thus, the histology of the anterior kidney of specimens from the Tapee river, Chawang district, Nakhon Si ...
Sinlapachai SENARAT, Jes KETTRATAD, Pisit POOLPRASERT, Watiporn YENCHUM   +3 more
doaj   +1 more source