Results 141 to 150 of about 639,100 (318)
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Elimination In Vivo of Developing T Cells by Natural Killer Cells [PDF]
Natural killer cells gauge the absence of self class I MHC on susceptible target cells by means of inhibitory receptors such as members of the Ly49 family.
Bonasio, Roberto+2 more
core +2 more sources
Supercompliant Lattice Boosts n‐type AgSbTe2 Thermoelectrics
The supercompliant lattice design enables the first realization of n‐type electrical transport in AgSbTe2 by overcoming intrinsic electron‐killer defects and exceeding the doping limits imposed by the conventional Hume–Rothery rule. Accordingly, the best performance n‐type Ag0.8Na0.3Sb0.6Bi0.4Te2 sample achieves a low κ of 0.27 W·m−1·K−1 that ...
Ruoyan Li+15 more
wiley +1 more source
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma+10 more
wiley +1 more source
The Design Space of Social Robots [PDF]
We consider the design space available for social robots in terms of a hierarchy of functional definitions: the essential properties in terms of a locus of interaction, autonomy, intelligence, awareness of humans as possessors of mental state, and awareness of humans as social interactors.
arxiv
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
Can persistent Epstein-Barr virus infection induce Chronic Fatigue Syndrome as a Pavlov reflex of the immune response? [PDF]
Chronic Fatigue Syndrome is a protracted illness condition (lasting even years) appearing with strong flu symptoms and systemic defiances by the immune system. Here, by means of statistical mechanics techniques, we study the most widely accepted picture for its genesis, namely a persistent acute mononucleosis infection, and we show how such infection ...
arxiv
A hollow‐structured Fe3O4@AgAu@PDA‐ZnPc nanosphere has been developed, exhibiting controllable catalytic activity and “photothermal‐photodynamic‐Ag+” coupling antibacterial characteristics. When subjected to a rotating magnetic field, these performances are uniquely enhanced by magnetic propulsion, allowing the nanosphere to function as a magnetic ...
Jing Wang+7 more
wiley +1 more source