Results 221 to 230 of about 215,240 (265)
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Hospital Practice, 1982
Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
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Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
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Natural killer cells and natural killer T cells
Arthritis & Rheumatism, 2000NK cells are important in protecting against viral infections, and they may regulate the immune response. They are activated by hematopoietic blasts and pose a barrier to bone marrow transplantation. They are also abundant in the pregnant uterine decidua, although their role there is unknown.
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Current Hematologic Malignancy Reports, 2009
The natural killer (NK)-cell neoplasms are rare, representing less than 1% of non-Hodgkin lymphoma, except in Asia and Latin America, where they represent 3% to 6%. NK-cell neoplasms include immature acute leukemias; a blastic NK-cell lymphoma, which is obsolete because of its plasmacytoid dendritic-cell origin; and mature NK neoplasms, comprising ...
John P, Greer, Claudio A, Mosse
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The natural killer (NK)-cell neoplasms are rare, representing less than 1% of non-Hodgkin lymphoma, except in Asia and Latin America, where they represent 3% to 6%. NK-cell neoplasms include immature acute leukemias; a blastic NK-cell lymphoma, which is obsolete because of its plasmacytoid dendritic-cell origin; and mature NK neoplasms, comprising ...
John P, Greer, Claudio A, Mosse
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Current Opinion in Immunology, 1995
In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that appear to utilize the same inhibitory signaling ...
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In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that appear to utilize the same inhibitory signaling ...
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Current Opinion in Immunology, 1997
The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural killer cells involves two different types of receptors ...
E O, Long, N, Wagtmann
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The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural killer cells involves two different types of receptors ...
E O, Long, N, Wagtmann
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Improving natural killer cells
Cytotherapy, 2008Donor lymphocyte infusions after stem cell transplantation have taught the cancer community that human immune cells have the potential power to control growth of and even eliminate a malignant clone. Although infusion of allogeneic T lymphocytes after stem cell transplantation has become part of the treatment algorithm, either to prevent or treat ...
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Natural killer and natural killer-T cells in psoriasis
Archives of Dermatological Research, 2002Psoriasis is characterized by a dermal and epidermal infiltrate comprised predominantly of CD4(+) and CD8(+) T cells, respectively. These cells behave in an antigen-dependent manner, which suggests that psoriasis may be a T-cell-mediated autoimmune disease.
Cameron, A. +3 more
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1996
Natural Killer (NK) cells represent a distinct lymphoid lineage. These cells were initially defined functionally by their ability to kill certain virally infected cells and tumor cells (reviewed in Trinchieri 1989; Ritz et al. 1988). This unique function and its evolutionary conservation led to the classification of NK cells as part of the innate ...
T W, Göbel, C H, Chen, M D, Cooper
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Natural Killer (NK) cells represent a distinct lymphoid lineage. These cells were initially defined functionally by their ability to kill certain virally infected cells and tumor cells (reviewed in Trinchieri 1989; Ritz et al. 1988). This unique function and its evolutionary conservation led to the classification of NK cells as part of the innate ...
T W, Göbel, C H, Chen, M D, Cooper
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2008
Natural killer (NK) cells are an important arm of the innate immune response that are directly involved in the recognition and lysis of virus-infected and tumor cells. Such function is under the control of a complex array of germline-encoded receptors able to deliver either inhibitory or activating signals.
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Natural killer (NK) cells are an important arm of the innate immune response that are directly involved in the recognition and lysis of virus-infected and tumor cells. Such function is under the control of a complex array of germline-encoded receptors able to deliver either inhibitory or activating signals.
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Immunoregulatory natural killer cells
Clinica Chimica ActaThis review discusses a broader scope of functional roles for NK cells. Despite the well-known cytolytic and inflammatory roles of NK cells against tumors and pathogenic diseases, extensive evidence demonstrates certain subsets of NK cells have defacto immunoregulatory effects and have a role in inducing anergy or lysis of antigen-activated T cells and
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