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Natural killer cells and natural killer T cells
Arthritis & Rheumatism, 2000NK cells are important in protecting against viral infections, and they may regulate the immune response. They are activated by hematopoietic blasts and pose a barrier to bone marrow transplantation. They are also abundant in the pregnant uterine decidua, although their role there is unknown.
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Natural killer cells and malaria
Immunological Reviews, 2006Summary: Malaria, caused by the infection with parasites of the germs Plasmodium, is one of the three most important infectious diseases worldwide, along with tuberculosis and infection with human immunodeficiency virus. Natural killer (NK) cells are lymphocytes classically involved in the early defense against viral infections and intracytoplasmic ...
Roetynck, Sophie +5 more
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Hospital Practice, 1982
Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
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Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
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CRC Critical Reviews in Clinical Laboratory Sciences, 1985
It is proposed that this article will encompass a review of primarily the human natural killer cell. The following parameters of the human natural killer (NK) cell will be reviewed: its ontogeny; surface membrane characteristics including monoclonal antibody reactivity, cell lineage, the natural killer sensitive targets, and the proposed mechanism of ...
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It is proposed that this article will encompass a review of primarily the human natural killer cell. The following parameters of the human natural killer (NK) cell will be reviewed: its ontogeny; surface membrane characteristics including monoclonal antibody reactivity, cell lineage, the natural killer sensitive targets, and the proposed mechanism of ...
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Trafficking of Natural Killer Cells
Current Molecular Medicine, 2004Natural killer (NK) cells comprise a set of lymphocytes that is capable of mediating innate immune responses to viral infections, malignancies, and allogeneic bone marrow grafts. This review summarizes what is known about the mechanisms NK cells use to arrive at their sites of action.
M A, Morris, K, Ley
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Nature Immunology, 2011
Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role in immune defense against viral and bacterial infections and malignancies. NK cells are traditionally defined as cells of the innate immune response because they lack RAG recombinase–dependent clonal antigen receptors.
Silke, Paust, Ulrich H, von Andrian
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Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role in immune defense against viral and bacterial infections and malignancies. NK cells are traditionally defined as cells of the innate immune response because they lack RAG recombinase–dependent clonal antigen receptors.
Silke, Paust, Ulrich H, von Andrian
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Natural killer cell metabolism
Molecular Immunology, 2019Natural killer (NK) cells are a critical component in the innate immune response against disease. NK cell function is tightly regulated by specific cytokine and activation/inhibitory receptor signalling, leading to diverse effector responses. Like all living cells, energy metabolism is a fundamental requirement for NK cell activation and survival ...
Kobayashi, Takumi +1 more
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Natural killer cells and reproduction
Trends in Immunology, 2002Abstract The Cambridge Immunology and Reproductive Immunology Groups of the British Society for Immunology held a meeting on NK Cells and Reproduction at King's College, Cambridge, UK, on 2–4 April, 2002.
Ashley, Moffett-King +4 more
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Natural Killer Cells and Cancer
2003Natural killer (NK) cells are lymphocytes that were first identified for their ability to kill tumor cells without deliberate immunization or activation. Subsequently, they were also found to be able to kill cells that are infected with certain viruses and to attack preferentially cells that lack expression of major histocompatibility complex (MHC ...
Jun, Wu, Lewis L, Lanier
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Natural killer cells in cancer
Seminars in Cancer Biology, 2006Publisher Summary Integrated with other immune cells, natural killer (NK) cells contribute to host anti-microbial and anti- tumor immunity. The provision of early defence mechanisms against viral infections, particularly herpes viruses, is perhaps the most important clinical effect by NK cells, but it was their cytotoxic potency against tumor cells ...
Petter, Höglund, Eva, Klein
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