Results 201 to 210 of about 2,346,598 (263)

JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection. [PDF]

Virus Res
Chen N, Jin J, Qiao B, Gao Z, Tian Y, Ping J.   +5 more
europepmc   +1 more source

HGF/c‐Met Axis‐Targeted Nanotherapy via GSH‐Responsive Polymer Platforms Suppresses Uveal Melanoma Metastasis

Advanced Healthcare Materials, EarlyView.
To suppress uveal melanoma metastasis (UM), the GSH‐responsive polymer named NP@Oxa/Criz has been successfully prepared. NP@Oxa/Criz selectively accumulates in UM tumors, targeting HGF/c‐Met Axis to undermine the stemness and metastasis of UM while triggering immunogenic cell death through DAMPs release to boost anti‐tumor immunity.
Hui Tao, Hanhan Liu, Hanchen Zhang, Hong Ren, Binyu Wen, Jing Zhang, Jiaqi Du, Ziyi Cai, Zhihong Deng   +8 more
wiley   +1 more source

Identification of Novel HPK1 Hit Inhibitors: From In Silico Design to In Vitro Validation. [PDF]

Int J Mol Sci
Isawi IH, Obeidat RM, Alnabulsi S, Al Zoubi R.   +3 more
europepmc   +1 more source

Controlled Magnesium Ion Delivery via Mg‐Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim, Jieun Kwon, Hyeok Kim, Sunhee Lee, Seongchan Kim, Ji‐Young Lee, Khandoker Asiqur Rahaman, Taeyeon Kim, Hyojin Lee, Myoung‐Ryul Ok, Seok Chung, Hyung‐Seop Han, Yu‐Chan Kim   +12 more
wiley   +1 more source

Biological functionality of non-functional protein kinases. [PDF]

J Exp Bot
Joosten MHAJ.
europepmc   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Statement of Retraction: The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway. [PDF]

Bioengineered
europepmc   +1 more source

Efficacy and Safety of Syk and BTK Inhibitors in Immune Thrombocytopenia: A Comprehensive Review of Emerging Evidence. [PDF]

Mediators Inflamm
Heidari A, Mazid AS, Behroozfar M, Ghotbi N, Fathabadi F, Eghbali S, Heidari N.   +6 more
europepmc   +1 more source

Pediatric Cutaneous Anaplastic Lymphoma Kinase-Positive Histiocytosis with <i>DCTN1::ALK</i> Fusion: A Case Report and Literature Search. [PDF]

Diagnostics (Basel)
Korpás KL, Mokánszki A, Beke L, Méhes G, Chang Chien YC.   +4 more
europepmc   +1 more source

The advances in acetylation modification in senescence and aging-related diseases. [PDF]

Front Physiol
Xu M, Wang W, Lu S, Xiong M, Zhao T, Yu Y, Song C, Yang J, Zhang N, Cao L, Sun G, Chen S, Wang P.   +12 more
europepmc   +1 more source