Results 131 to 140 of about 51,301 (248)

A frontal lobe mass in a 6‐year‐old girl

Brain Pathology, EarlyView.
Francesca S. Vacca, Aaron Mochizuki, Smruti K. Patel, Blaise Jones, Somak Roy, Kirti Gupta   +5 more
wiley   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2794-2803, December 2026.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula, Juvy Rabelas, Kareem Touleimat, Elaine Marchi, Ruhi Shah, Shaydah Kheradmand, Kuldeep Singh, Karen Amble, Gholson J. Lyon   +8 more
wiley   +1 more source

Pathogenicity of NUSAP1 Variants Is Defined by NMD‐Escape: Evidence From Two Novel Cases and Systematic Population‐Based Variant Analysis

Clinical Genetics, Volume 110, Issue 6, Page 768-774, December 2026.
Heterozygous de novo nonsense variants in the penultimate and last exons of NUSAP1 were identified in two unrelated individuals, predicted to escape NMD. In population data, nonsense variants were observed in exons 1–9 (of 11) in NUSAP1 but were absent from its 3′‐terminal region.
Maureen Jacob, Susann Badmann, Stefania Bigoni, Maria Iascone, Ilaria Vivaldi, Katharina Mayerhanser, Robert Kopajtich, Holger Prokisch, Cristina Forest, Sebastian Eck, Michael Zech, Elisabeth Graf, Matias Wagner, Juliane Winkelmann, Theresa Brunet, Melanie Brugger   +15 more
wiley   +1 more source

Beyond Membrane Fusion: SNARE Proteins as Regulators of Signaling and Gene Expression

Traffic, Volume 27, Issue 4, December 2026.
Regulation of gene expression by SNAREs. Some SNAREs, including alternatively spliced isoforms, may access the nucleus where they perform various regulatory activities. These SNAREs may act as transcriptional activators or mediate/participate in the transport of transcription factors to the nucleus.
Clémentine Roux, Albert Descoteaux
wiley   +1 more source

Two Tetrahymena kinesin-9 family members exhibit slow plus-end-directed motility in vitro

Scientific Reports
The kinesin-9 family comprises two subfamilies specific to ciliated eukaryotic cells, and has recently attracted considerable attention because of its importance in ciliary bending and formation.
Hiroto Ishii, Masahiko Yamagishi, Junichiro Yajima   +2 more
doaj   +1 more source

Lost and Found: Western Honey Bee (Apis mellifera) Matrix Metalloproteinase 1

Ecology and Evolution, Volume 16, Issue 11, November 2026.
Despite considerable overall improvements in the Western honey bee (Apis mellifera) reference genome over the past two decades, some genes are missing in the current reference assembly (Amel_HAv3.1), potentially interfering with the meaningfulness of downstream analyses.
Jessica Braunisch, Ken Werner, Ulrich R. Ernst, Christian W. W. Pirk, Anja Buttstedt   +4 more
wiley   +1 more source

A moving kinesin motor protein

, 2014
Shows two heads of the kinesin dimer work in a coordinated manner to move processively along the track. The coiled coil (gray) extends towards the top and leads up to the kinesin cargo. Each catalytic core (blue) is bound to a tubulin heterodimer (green,
Vale, Ronald D., Milligan, Ronald A.
core  

The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System

Glia, Volume 74, Issue 11, November 2026.
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada, Hinako Saito, Riko Takahashi, Mio Fujisato, Yukina Hosoda, Binri Sasaki, Momona Yamada, Sakurako Abe, Chikako Hayashi, Akira Yoshimoto, Ryunosuke Ohkawa, Tomal Julian Matt, Florence M Bareyre, Stefan Berghoff, Mikael Simons, Nobuharu Suzuki   +15 more
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Speed Control of Single Molecules on a Surface

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
The speed of a single molecule moving across a silver crystal surface is determined with the tip of a scanning tunneling microscope (STM). Travelling distances Δx and travelling times Δt, which are determined simultaneously with high precision, allow to directly measure time–distance relationships.
Donato Civita, Matthew J. Timm, Julia Lanz, Christophe Nacci, Stefan Hecht, Leonhard Grill   +5 more
wiley   +2 more sources