Results 111 to 120 of about 47,063 (259)
Journal of the Chinese Chemical Society, EarlyView.Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
PLoS Genetics, 2012 Hereditary spastic paraplegias (HSPs) comprise a group of genetically heterogeneous neurodegenerative disorders characterized by spastic weakness of the lower extremities.
Petra Füger +12 more
doaj +1 more source
Chapter 4 The Kinesin-3 Family [PDF]
, 2020 The Kinesin-3s are a family of cargo transporters. They typically display highly processive plus-end-directed motion, either as dimers or in teams, formed via interaction with ...
Siddiqui, Nida, Straube, Anne
core
Journal of the Chinese Chemical Society, EarlyView.The conventional “local activation–global inhibition” (LAGI) models utilize mean‐field averaging inhibition to suppress distant activations. As the inhibition diminishes with distance, LAGI models struggle to achieve robust single‐axis polarity in large systems.
Chin‐Lin Guo, Chiao‐Yu Tseng
wiley +1 more source
Kinesin-II-associated intraflagellar transport particles contain large protein complexes
, 1998 Kinesin-II-associated intraflagellar transport particles contain large protein ...
J Fuster (13719088) +5 more
core +1 more source
The role of casein in supporting the operation of surface bound kinesin
Journal of Biological Engineering, 2008 Microtubules and associated motor proteins such as kinesin are envisioned for applications such as bioseparation and molecular sorting to powering hybrid synthetic mechanical devices.
Hancock William O +2 more
doaj +1 more source
Kinesin-Driven Active Substrate Giving Stochastic Mechanical Stimuli to Cells for Characterization
, 2016 We present a new platform to give stochastic mechanical stimuli to cells for their characterization. There nano- and micrometer scaled fluctuations are generated by an engineered motor protein system of kinesin-microtubules (MTs) on a solid surface ...
Hiroshi Y. Yoshikawa (1304850) +4 more
core +1 more source
Bottom‐Up Synthesis and Active Assembly of DNA Networks by Biomolecular Nanomachines
Small, EarlyView.This study demonstrates a dynamic, bottom‐up assembly of DNA materials driven by two biomolecular nanomachines: DNA polymerase and kinesin. Through sequential chemical synthesis and motor‐driven mechanical manipulation, DNA fibrous networks are dynamically formed with complex morphologies unattainable by self‐assembly alone.
Farhana Afroze +11 more
wiley +1 more source
Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s
Nature Communications, 2018 Kinesin-13s are microtubule depolymerases that lack motile activity. Here the authors present the cryo-EM structures of kinesin-13 microtubule complexes in different nucleotide bound states, which reveal how ATP hydrolysis is linked to conformational ...
Matthieu P.M.H. Benoit +2 more
doaj +1 more source