Results 111 to 120 of about 38,190 (209)

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

open access: yeseFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu   +4 more
wiley   +1 more source

High‐throughput mutational analysis of F1‐ATPase by integrated cell‐free protein synthesis and single‐molecule rotation assay

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract F1‐ATPase (F1) is a rotary molecular motor that hydrolyzes adenosine triphosphate (ATP) to drive rotation of the central subunit against the surrounding stator ring. Single‐molecule rotation assays of mutated F1s have elucidated the roles of residues and regions in the chemo‐mechanical coupling mechanism, yet comprehensive mutational ...
Mai Taguchi   +3 more
wiley   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 5120-5147, August 2026.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

Size of chloroplasts in Arabidopsis mesophyll cells affects jasmonate biosynthesis

open access: yesPlant Biology, Volume 28, Issue 5, Page 1330-1342, August 2026.
The relationship between chloroplast structure and hormone biosynthesis capacity is poorly understood. This study shows that mutants harbouring giant chloroplasts produce more jasmonic acid upon mechanical stress than wild‐type plants, suggesting that organellar architecture is a previously unrecognized factor associated with plant hormone biosynthesis
R. Baral   +6 more
wiley   +1 more source

Selective targeting of kinesin on lipid droplets in the liver reduces plasma lipids. [PDF]

open access: yesProc Natl Acad Sci U S A
Tripathy SK   +7 more
europepmc   +1 more source

Motor Protein Disruption Critically Alters Organelle Trafficking and Excitation-Contraction Coupling. [PDF]

open access: yeseNeuro
Bansal H   +5 more
europepmc   +1 more source

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