Results 121 to 130 of about 82,635 (293)

Connecting neurodevelopment to neurodegeneration: a spotlight on the role of kinesin superfamily protein 2A (KIF2A)

Neural Regeneration Research
Microtubules play a central role in cytoskeletal changes during neuronal development and maintenance. Microtubule dynamics is essential to polarity and shape transitions underlying neural cell division, differentiation, motility, and maturation.
Nuria Ruiz-Reig, Janne Hakanen, Fadel Tissir   +2 more
doaj   +1 more source

KIF26A Is an Unconventional Kinesin and Regulates GDNF-Ret Signaling in Enteric Neuronal Development [PDF]

, 2009
Ruyun Zhou, Shinsuke Niwa, Noriko Homma, Yosuke Takei, Nobutaka Hirokawa   +4 more
openalex   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Mechanics of Kinesin-Crosslinked Microtubule Networks [PDF]

, 2014
Yali Yang, Megan T. Valentine
openalex   +1 more source

Huntingtin as an Actin Organizer: Structural and Functional Insights

Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley   +1 more source

Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

Traffic, Volume 27, Issue 2, June 2026.
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano, Vera Egorova, José Villanueva, Luis Miguel Gutiérrez, Virginia González‐Vélez, Amparo Gil, Sandra Jurado   +6 more
wiley   +1 more source

Cross-Species Analysis of Kinesin-14s: Human HSET Functions in Fission Yeast to Regulate Spindle Bipolarity [PDF]

, 2009
Dimitre R. Simeonov, Katelyn Kenny, Amanda Moyer, Janet L. Paluh   +3 more
openalex   +1 more source

Relationship Between Filament‐Polymerizing Muscle Myosin and Droplets Generated by Liquid–Liquid Phase Separation

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
A droplet formed by liquid–liquid phase separation (LLPS) that has deformed and even developed a protrusion due to the inclusion of meshwork structures formed by the assembly of myosin filaments. So far, such droplet deformation has not been observed and was not possible with either DNA or actin filaments.
Tatsuyuki Waizumi, Mahito Kikumoto, Tomoharu Matsumoto, Kingo Takiguchi   +3 more
wiley   +1 more source

Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B

Scientific Reports, 2018
Bardet-Biedl syndrome (BBS) is a ciliopathy characterized by retinal degeneration, obesity, polydactyly, renal disease and mental retardation. CCDC28B is a BBS-associated protein that we have previously shown plays a role in cilia length regulation ...
Rossina Novas, Magdalena Cardenas-Rodriguez, Paola Lepanto, Matías Fabregat, Magela Rodao, María Inés Fariello, Mauricio Ramos, Camila Davison, Gabriela Casanova, Lucía Alfaya, Federico Lecumberry, Gualberto González-Sapienza, Florencia Irigoín, Jose L. Badano   +13 more
doaj   +1 more source

Microfluidic Device to Measure Collective Force Dynamics of Kinesin Motor Proteins [PDF]

, 2018
Joseph M. Cleary, William O. Hancock
openalex   +1 more source