Results 101 to 110 of about 47,063 (259)
A moving kinesin motor protein
, 2016 Shows two heads of the kinesin dimer work in a coordinated manner to move processively along the track. The coiled coil (gray) extends towards the top and leads up to the kinesin cargo. Each catalytic core (blue) is bound to a tubulin heterodimer (green,
Vale, Ronald D., Milligan, Ronald A.
core +1 more source
Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin
Nature Communications, 2017 Kinesin-13s are microtubule depolymerizing enzymes. Here the authors present the crystal structure of a DARPin fused construct comprising the short neck region and motor domain of kinesin-13 in complex with an αβ-tubulin heterodimer, which shows that ...
Weiyi Wang +6 more
doaj +1 more source
iMetaOmics, EarlyView.Paradigm shift: PCR‐free methods reveal 6–15‐fold higher arbuscular mycorrhizal (AM) fungal abundance than metabarcoding, exposing systematic underestimation across decades of research. Predictive power: AM fungal abundance serves as a community‐level trait that predicts crop yield under drought conditions.
Peilin Chen, John W. Taylor, Cheng Gao
wiley +1 more source
Nature CommunicationsHeterotrimeric kinesin-2, composed of two distinct kinesin motors and a kinesin-associated protein (KAP), is essential for intraflagellar transport and ciliogenesis.
Jinqi Ren +4 more
doaj +1 more source
BMC Research Notes, 2009 Background Kinesin-5 (Eg-5) motor proteins are essential for maintenance of spindle bipolarity in animals. The roles of Kinesin-5 proteins in other systems, such as Arabidopsis, Dictyostelium, and sea urchin are more varied.
Miller Anne +2 more
doaj +1 more source
The Journal of Cell Biology, 2007 When it is not actively transporting cargo, conventional Kinesin-1 is present in the cytoplasm in a folded conformation that cannot interact effectively with microtubules (MTs). Two important and largely unexplored aspects of kinesin regulation are how it is converted to an active species when bound to cargo and the related issue of how kinesin ...
openaire +2 more sources
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Mechanism of Processive Movement of Monomeric and Dimeric Kinesin Molecules
International Journal of Biological Sciences, 2010 Kinesin molecules are motor proteins capable of moving along microtubule by hydrolyzing ATP. They generally have several forms of construct. This review focuses on two of the most studied forms: monomers such as KIF1A (kinesin-3 family) and dimers such ...
Ping Xie
doaj
Simulating the kinesin walk : towards a definitive theory [PDF]
Dementia is a set of incurable, fatal diseases characterised by irreversible degeneration of the brain. One theory of its cause is the failure of intracellular transport in the axons of the neurons that compose the brain.
Wilson, Richard John
core
Kinesin-8X shows ATPase, gliding motor and depolymerization activities.
, 2019 (A) Schematic protein organisation of PBANKA_0805900 (Pbkinesin-8X) and PF3D7_0319400 (Pfkinesin-8X) showing their full-length sequence and central location of the motor domain, Pbkinesin-8X (green) and Pfkinesin-8X (blue).
Edward Rea (7484642) +17 more
core +1 more source