Results 101 to 110 of about 51,301 (248)
Spatial Gene Expression in Fungi: mRNA Localization, Condensates, and Beyond
Yeast, EarlyView.ABSTRACT Polarized growth and cellular asymmetry are broadly conserved properties of fungal life, from transient bud‐site selection in unicellular yeasts to sustained hyphal extension in filamentous and coenocytic species. While vesicle trafficking, cytoskeletal organization, and cell‐wall remodeling are well‐established contributors to these processes,
Sander van Otterdijk +3 more
wiley +1 more source
Nature CommunicationsHeterotrimeric kinesin-2, composed of two distinct kinesin motors and a kinesin-associated protein (KAP), is essential for intraflagellar transport and ciliogenesis.
Jinqi Ren +4 more
doaj +1 more source
Integrative Zoology, EarlyView.A quantum‐enhanced weighted gene co‐expression network analysis framework integrating quantum amplitude amplification is developed to overcome sample size constraints in zoological genomics. This noise‐tolerant analytical strategy enables robust network reconstruction for non‐model species with limited biological replicates.
Seok‐Jin Kang, Hongchul Shin
wiley +1 more source
Mechanism of Processive Movement of Monomeric and Dimeric Kinesin Molecules
International Journal of Biological Sciences, 2010 Kinesin molecules are motor proteins capable of moving along microtubule by hydrolyzing ATP. They generally have several forms of construct. This review focuses on two of the most studied forms: monomers such as KIF1A (kinesin-3 family) and dimers such ...
Ping Xie
doaj
Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin
Nature Communications, 2017 Kinesin-13s are microtubule depolymerizing enzymes. Here the authors present the crystal structure of a DARPin fused construct comprising the short neck region and motor domain of kinesin-13 in complex with an αβ-tubulin heterodimer, which shows that ...
Weiyi Wang +6 more
doaj +1 more source
BMC Research Notes, 2009 Background Kinesin-5 (Eg-5) motor proteins are essential for maintenance of spindle bipolarity in animals. The roles of Kinesin-5 proteins in other systems, such as Arabidopsis, Dictyostelium, and sea urchin are more varied.
Miller Anne +2 more
doaj +1 more source
The Journal of Cell Biology, 2007 When it is not actively transporting cargo, conventional Kinesin-1 is present in the cytoplasm in a folded conformation that cannot interact effectively with microtubules (MTs). Two important and largely unexplored aspects of kinesin regulation are how it is converted to an active species when bound to cargo and the related issue of how kinesin ...
openaire +2 more sources
Brain Pathology, EarlyView.In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles +15 more
wiley +1 more source
Kinetic and mechanistic basis of the nonprocessive Kinesin-3 motor NcKin3
, 2006 Kinesin-3 motors have been shown to transport cellular cargo along microtubules and to function according to mechanisms that differ from the conventional hand-over-hand mechanism.
Woehlke, G. +11 more
core +1 more source