Results 81 to 90 of about 82,635 (293)

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

A model for hand-over-hand motion of molecular motors

, 2008
A simple flashing ratchet model in two dimensions is proposed to simulate the hand-over-hand motion of two head molecular motors like kinesin. Extensive Langevin simulations of the model are performed.
E. Helfand, F. Falo, H. S. Greensidea, J. Howard, J. J. Mazo, J. Munárriz, P. Nelson   +6 more
core   +1 more source

A standardized kinesin nomenclature [PDF]

The Journal of Cell Biology, 2004
In recent years the kinesin superfamily has become so large that several different naming schemes have emerged, leading to confusion and miscommunication. Here, we set forth a standardized kinesin nomenclature based on 14 family designations. The scheme unifies all previous phylogenies and nomenclature proposals, while allowing individual sequence ...
Lawrence, Carolyn J, Dawe, R Kelly, Christie, Karen R, Cleveland, Don W, Dawson, Scott C, Endow, Sharyn A, Goldstein, Lawrence SB, Goodson, Holly V, Hirokawa, Nobutaka, Howard, Jonathon, Malmberg, Russell L, McIntosh, J Richard, Miki, Harukata, Mitchison, Timothy J, Okada, Yasushi, Reddy, Anireddy SN, Saxton, William M, Schliwa, Manfred, Scholey, Jonathan M, Vale, Ronald D, Walczak, Claire E, Wordeman, Linda   +21 more
openaire   +4 more sources

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, EarlyView.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Nature Communications, 2017
Bipolar spindle assembly requires a balance of kinesin 14 pulling and kinesin 5 pushing forces. Here, the authors show that in fission yeast, spindle formation can occur in the absence of kinesin 5 (Cut7) and 14 (Pkl1) but requires the microtubule ...
Sergio A. Rincon, Adam Lamson, Robert Blackwell, Viktoriya Syrovatkina, Vincent Fraisier, Anne Paoletti, Meredith D. Betterton, Phong T. Tran   +7 more
doaj   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

, 2015
Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large.
Appert-Rolland, Cecile, Ebbinghaus, Maximilian, Santen, Ludger   +2 more
core   +3 more sources

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Realistic Models of Biological Motion

, 1998
The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule.
Ajdari, Ajdari, Ajdari, Astumian, Astumian, Cooke, Cooke, Doering, Edman, Eisenberg, Faucheux, Faucheux, Finer, Gilbert, Goldman, Harada, Hill, Hirose, Hoenger, Hunt, Huxley, Huxley, Imre Derényi, Katz, Kikkawa, Kron, Kull, Leibler, Lymn, Magnasco, Millonas, Millonas, Pate, Pate, Rayment, Rousselet, Sablin, Sleep, Svoboda, Svoboda, Svoboda, Tamás Vicsek, Vale   +42 more
core   +1 more source