Results 91 to 100 of about 47,063 (259)

KIF14 and citron kinase act together to promote efficient cytokinesis [PDF]

, 2006
Multiple mitotic kinesins and microtubule-associated proteins (MAPs) act in concert to direct cytokinesis (Glotzer, M. 2005. Science. 307:1735-1739). In anaphase cells, many of these proteins associate with an antiparallel array of microtubules termed ...
Erich A. Nigg, Chan, E. H. Y., Francis A. Barr, Eunice H.Y. Chan, Neef, Rüdiger, Nigg, EA, Xiuling Li, Rüdiger Neef, Gruneberg, Ulrike, Nigg, E. A., Gruneberg, U, Chan, EH, Chalamalasetty, R. B., Nigg, Erich A., Chalamalasetty, Ravindra B., Neef, R, Grüneberg, U., Chalamalasetty, RB, Barr, Francis A., Barr, FA, Li, Xiuling, Ravindra B. Chalamalasetty, Neef, R., Barr, F. A., Chan, Eunice H. Y., Ulrike Gruneberg, Li, X, Li, X. L.   +27 more
core   +1 more source

Kinesin-2 is necessary for Orco entry into the olfactory cilia.

, 2021
(A-D) Total fluorescence intensity (mean ± S.E.M) of Endo-Orco:GFP in the ciliary OS and the dendritic knob region of OSNs in Control (A), Klp64D RNAi (B), Klp68D RNAi (C) and homozygous Klp64Dkj353 mutant (D) backgrounds, respectively.
Akanksha Jain (153306), Anjusha Singh (11302598), Priya Dutta (535764), Swadhin Chandra Jana (9282665), Mukul Girotra (8963333), Seema Shirolikar (11302607), Lavanya Adusumilli (11302601), Diksha Kumari (11302604), Krishanu Ray (131985)   +8 more
core   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Dissection of Kinesin's Processivity

PLoS ONE, 2009
The protein family of kinesins contains processive motor proteins that move stepwise along microtubules. This mechanism requires the precise coupling of the catalytic steps in the two heads, and their precise mechanical coordination. Here we show that these functionalities can be uncoupled in chimera of processive and non-processive kinesins. A chimera
Sarah Adio, Johann Jaud, Bettina Ebbing, Matthias Rief, Günther Woehlke   +4 more
openaire   +4 more sources

Speed effects in gliding motility assays due to surface passivation, water isotope, and osmotic stress.

, 2010
The molecular motor kinesin-1, an ATPase, and the substrate it walks along, microtubules, are vital components of eukaryotic cells. Kinesin converts chemical energy to linear motion as its two motor domains step along microtubules in a process similar to
Steven J. Koch, Andy Maloney, Lawrence J. Herskowitz   +2 more
core   +1 more source

miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]

, 2012
Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Cuppen, E., Bernhard Brüne, David Sáenz-Morales (139779), Konstantinos Stamatakis (139787), Stamatakis, K., Ramos, Edurne, Elisa Conde, Edurne Ramos (139777), Ramos, E., García Bermejo, María Laura, Blanco-Sanchez, I., Edwin Cuppen, Sáenz-Morales, David, Brune, B., Conde, E., Ignacio Blanco-Sánchez (139784), Bermejo, M.L., Luis del Peso (133134), Edwin Cuppen (9902), Stamatakis Andriani, Konstantinos, Stamatakis, Konstantinos, Peso, Luis del, del Peso, Luis, María Laura García Bermejo (139790), Saenz-Morales, D., Conde, Elisa, Konstantinos Stamatakis, María Laura García Bermejo, Edurne Ramos, Aguado-Fraile, Elia, Aguado-Fraile, E., del Peso, L., Ignacio Blanco-Sánchez, Blanco-Sánchez, Ignacio, Brüne, Bernhard, Bernhard Brüne (131193), Cuppen, Edwin, Elia Aguado-Fraile (139775), Elisa Conde (139781), Elia Aguado-Fraile, Luis del Peso, David Sáenz-Morales   +41 more
core   +1 more source

The location of kinesin-5 and kinesin-8X in relation to that of kinetochore (NDC80) and axoneme marker (kinesin-8B).

, 2022
(A) Live cell images of gametocytes showing dual lines expressing either kinesin-5GFP or NDC80-mCherry/kinesin-8BmCherry or both in the same gametocyte.
Anthony A. Holder (53358), Rita Tewari (134257), Sue Vaughan (20216), Steven Abel (7484636), Zeinab Chahine (13170045), Ravish Rashpa (4278514), Mohammad Zeeshan (141644), Carolyn A. Moores (7484654), Karine G. Le Roch (7373171), David J. P. Ferguson (7484639), Declan Brady (134247), Mathieu Brochet (149272)   +11 more
core   +1 more source

C‐Terminal Tail Elongation Adds a New Dimension to the Tubulin Code

Cytoskeleton, EarlyView.
ABSTRACT Tubulin C‐terminal tails undergo diverse post‐translational modifications that regulate microtubule interactions with motors and severing enzymes. TTLL11, a member of the tubulin tyrosine ligase‐like (TTLL) family, uniquely catalyzes glutamate addition to the terminal α‐carboxyl group of both α‐ and β‐primary tubulin tails.
Jana Campbell, Cyril Barinka
wiley   +1 more source

A moving kinesin motor protein

, 2013
Shows two heads of the kinesin dimer work in a coordinated manner to move processively along the track. The coiled coil (gray) extends towards the top and leads up to the kinesin cargo. Each catalytic core (blue) is bound to a tubulin heterodimer (green,
Vale, Ronald D., Milligan, Ronald A.
core   +1 more source

Kinesin Regulation via Kinesin Binding Protein and Autoinhibition

, 2023
Cells are complex systems that continuously adapt and respond to their ever-changing environments. Integral to this adaptability is the precise organization and reorganization of cellular structures, among which the cytoskeleton plays a foundational role.
Tan, Zhenyu
core   +1 more source