Results 171 to 180 of about 94,650 (353)

Local synaptic signaling enhances the stochastic transport of\ud motor-driven cargo in neurons [PDF]

, 2010
The tug-of-war model of motor-driven cargo transport is formulated as an intermittent trapping process. An immobile trap, representing the cellular machinery that sequesters a motor-driven cargo for eventual use, is located somewhere within a microtubule
Bressloff, P. C., Newby, J. M.
core  

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

Evolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross   +7 more
wiley   +1 more source

Short coiled‐coil proteins from plants and metazoans – the ‘jacks of all trades’

The FEBS Journal, EarlyView.
Short coiled‐coil proteins from plants and metazoans—true ‘jacks of all trades’—play supporting but crucial roles in cellular stress response, metabolism, autophagy, and membrane dynamics. Despite their small size and modest sequence conservation, proteins like plant LSUs and metazoan SCOCs showcase remarkable functional versatility shaped by evolution,
Agnieszka Sirko, Jarosław Poznański, Marzena Sieńko   +2 more
wiley   +1 more source

Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins. [PDF]

, 1992
R D Vale, Fady I. Malik, David T. Brown
openalex   +1 more source

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation

The FEBS Journal, EarlyView.
Activation of CLIP170 by CDKL5 in wild‐type (WT) cells promotes its open conformation and association with tyrosinated microtubule (MT) plus‐ends (+), where it works as a docking site to recruit the dynactin–dynein–cargo complex, promoting the initiation of retrograde transport. In knock‐out (KO) neurons, CLIP170 is mainly present in a closed (inactive)
Serena Baldin, Clara Carmone, Giorgia Valetti, Roberta De Rosa, Isabella Barbiero   +4 more
wiley   +1 more source

Effects of Kinesin Mutations on Neuronal Functions [PDF]

, 1992
Michel Gho, Kent McDonald, Barry Ganetzky, W. M. Saxton   +3 more
openalex   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules. [PDF]

, 1992
Bruce J. Schnapp, Thomas S. Reese, Rolf Bechtold   +2 more
openalex   +1 more source

Gene Expression Divergence Between Locally Adapted Inland Annual and Coastal Perennial Ecotypes of Mimulus guttatus Across Developmental Stages

Molecular Ecology, EarlyView.
ABSTRACT The action of natural selection across heterogeneous natural landscapes drives local adaptation and the formation of plant ecotypes, the precursors to new species. Plant ecotypes typically differ significantly in morphology, physiology, and development, yet our understanding of their underlying genetic basis remains limited.
Jason D. Olsen, Billie A. Gould, Yani Chen, David B. Lowry   +3 more
wiley   +1 more source

Roles of kinesin and kinesin-like proteins in sea urchin embryonic cell division: evaluation using antibody microinjection. [PDF]

, 1993
Brent D. Wright, Mark Terasaki, Jonathan M. Scholey   +2 more
openalex   +1 more source