Results 91 to 100 of about 411,207 (359)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

CSP analysis of a transient flame-vortex interaction

open access: yes, 2003
The interaction of a two-dimensional counter-rotating vortex-pair with a premixed methane-air flame is analyzed with the Computational Singular Perturbation (CSP) method.
Goussis, D   +5 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Adsorption of peroxidase from L onto alginate–guar gum matrix: Kinetic, equilibrium and thermodynamic analysis

open access: yesAdsorption Science & Technology, 2016
This work explores the kinetics, equilibrium and thermodynamics of peroxidase adsorption onto spherical guar gum–alginate matrices. The effect of contact time, solution pH, initial protein concentration and temperature was studied in batch experiments ...
Ana C Santos Leite da Silva   +4 more
doaj   +1 more source

Physikalische Chemie der ionisierenden Strahlung

open access: yesCHIMIA, 1974
Physico-chemical aspects related to the interaction of ionizing radiation with matter are discussed. They are either specific problems of radiation, or general problems of chemical kinetics and spectroscopy, for which radiation serves as a tool ...
Rolf E. Bühler
doaj   +1 more source

Kinetics and mechanisms of the interaction between the calcite (10.4) surface and Cu2+-bearing solutions

open access: yes, 2019
Calcite dissolution, occurring in rocks, soils and sediments, is essential to indicate element cycles and local environments in the lithosphere, biosphere, hydrosphere and atmosphere.
Zhu, Jianxi   +6 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

An investigation into the behaviour, kinetics & mechanisms involved in the precipitation of a moderately soluble system

open access: yes, 2011
This dissertation consists of three interrelated sections dealing with: (i) Development of a suitable seed preparation technique, (ii) Determination of growth and aggregation kinetics and (iii) Determination of the induction ...
Musil, Emily Ann
core  

Determination of solvation kinetics in supercritical fluids. Summary report

open access: yes, 1993
Objective was to study solvation processes in pure and entrainer-modified supercritical fluids. Specific topics were: Kinetics for solvation in supercritical media, influence on entrainers on solvation, reversibility of solvation, effects of solvation on
Bright, F. V.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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