Results 71 to 80 of about 900,715 (293)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Adsorption Science & Technology, 2016 This work explores the kinetics, equilibrium and thermodynamics of peroxidase adsorption onto spherical guar gum–alginate matrices. The effect of contact time, solution pH, initial protein concentration and temperature was studied in batch experiments ...
Ana C Santos Leite da Silva +4 more
doaj +1 more source
Physikalische Chemie der ionisierenden Strahlung
CHIMIA, 1974 Physico-chemical aspects related to the interaction of ionizing radiation with matter are discussed. They are either specific problems of radiation, or general problems of chemical kinetics and spectroscopy, for which radiation serves as a tool ...
Rolf E. Bühler
doaj +1 more source
Evidence of Conformational Changes in Adsorbed Lysozyme Molecule on Silver Colloids
, 2010 In this article, we discuss metal-protein interactions in the Ag-lysozyme complex by spectroscopic measurements. The analysis of the variation in relative intensities of SERS bands reveal the orientation and the change in conformation of the protein ...
Chandra, Goutam +3 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Kinetical Foundations of Non Conventional Statistics
, 2001 After considering the kinetical interaction principle (KIP) introduced in ref. Physica A {\bf296}, 405 (2001), we study in the Boltzmann picture, the evolution equation and the H-theorem for non extensive systems.
A.M. Scarfone +10 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Research related to measurements of atomic species in the earth's upper atmosphere Final report [PDF]
Interaction kinetics of atomic oxygen and hydrogen on metal surfaces of satellite-borne mass ...
Baker, B. R., Wise, H., Wood, B. J.
core +1 more source