Results 61 to 70 of about 900,715 (293)

Dissipationless kinetics of one-dimensional interacting fermions [PDF]

Physical Review B, 2014
We study the problem of evolution of a density pulse of one-dimensional interacting fermions with a non-linear single-particle spectrum. We show that, despite non-Fermi-liquid nature of the problem, non-equilibrium phenomena can be described in terms of a kinetic equation for certain quasiparticles related to the original fermions by a non-linear ...
Protopopov, I. V., Gutman, D. B., Oldenburg, M., Mirlin, A. D.   +3 more
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Kinetics of lead interaction with human erythrocytes [PDF]

Postgraduate Medical Journal, 1975
SummaryThe kinetics of the interaction of lead with human erythrocytes has been investigated in vitro by means of tracer studies with 203Pb. The elution characteristics of lead from erythrocytes in contact with EDTA suggest the existence of two binding sites differing in their affinity for lead.
D, Barltrop, A M, Smith
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Self-consistent Approach to Off-Shell Transport

, 2003
The properties of two forms of the gradient expanded Kadanoff--Baym equations, i.e. the Kadanoff--Baym and Botermans-Malfliet forms, suitable to describe the transport dynamics of particles and resonances with broad spectral widths, are discussed in ...
C. G. Callan, C. Itzykson, D. N. Voskresensky, F. Jong de, G. Baym, G. Baym, G. M. Carneiro, J. Belinfante, J. Knoll, J. Knoll, J. Knoll, J. Schwinger, L. P. Kadanoff, L. P. Keldysh, M. Baldo, P. Bozek, P. Boźek, P. Danielewicz, P. Danielewicz, R. E. Norton, S. Leupold, S. T. Belyaev, T. Ericson, W. Botermans, W. Cassing, W. H. Dickhoff, Y. Dewulf, Yu. B. Ivanov, Yu. B. Ivanov, Yu. B. Ivanov, Yu. B. Ivanov   +30 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Kinetics of Filament Bundling with Attractive Interactions [PDF]

Biophysical Journal, 2004
We study the kinetics of filament bundling by variable time-step Brownian-dynamics simulations employing a simplified attractive potential based on earlier atomic-level calculations for actin filaments. Our results show that collisions often cluster in time, due to memory in the random walk. The clustering increases the bundling opportunities.
Yu, Xueping, Carlsson, A.E.
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Phonon-assisted relaxation kinetics of statistically-degenerate excitons in high-quality quantum wells

, 2001
Acoustic-phonon-assisted thermalization kinetics of excitons in quantum wells (QWs) is developed for small concentrations of particles, $\rho_{\rm 2D} \lesssim 10^9$ cm$^{-1}$, when particle-particle interaction can be neglected while Bose-Einstein ...
Ivanov, A. L., Soroko, A. V.
core   +1 more source