Results 61 to 70 of about 411,207 (359)
The performance of drug treatment and assessments of different drugs' side effects both can be affected by the interaction between food additives and drugs. Organic compounds such as food colorants dyes are utilized as additives in a wide range of foods.
Furat A. Hiawi, Inaam H. Ali
doaj +1 more source
Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity. [PDF]
The recruitment kinetics of double-strand break (DSB) signaling and repair proteins Mdc1, 53BP1 and Rad52 into radiation-induced foci was studied by live-cell fluorescence microscopy after ion microirradiation.
Hilmar Strickfaden (148181) +35 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Binding hotspots of BAZ2B bromodomain:histone interaction revealed by solution NMR driven docking [PDF]
Bromodomains are epigenetic reader domains, which have come under increasing scrutiny both from academic and pharmaceutical research groups. Effective targeting of the BAZ2B bromodomain by small molecule inhibitors has been recently reported, but no ...
Ferguson, Fleur M. +26 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Radon (Rn), a ubiquitous radioactive noble gas, is the main source of natural radiation to human and one of the major culprits for lung cancer. Reducing ambient Rn concentration by porous materials is considered as the most feasible and energy-saving ...
Yi Tao (178829) +20 more
core +3 more sources
Mathematical model of viral kinetics in vitro estimates the number of E2-CD81 complexes necessary for hepatitis C virus entry. [PDF]
Interaction between the hepatitis C virus (HCV) envelope protein E2 and the host receptor CD81 is essential for HCV entry into target cells. The number of E2-CD81 complexes necessary for HCV entry has remained difficult to estimate experimentally.
Pranesh Padmanabhan, Narendra M Dixit
doaj +1 more source
Critical damping in a kinetic interaction network [PDF]
In a kinetic interaction network, signals are emitted through motion. Natural examples include bird flocks, fish schools, and robot teams. A kinetic interaction network transmits information about external cues quickly and accurately. Analysis of a one-dimensional interaction network reveals a bound on the algebraic connectivity above which the ...
Derek A. Paley, Ajay K. Baharani
openaire +1 more source
Studies of the Effects of Co-substrates on Biodegradation Kinetics of 4-Chlorophenol Using Response Surface Methodology (RSM) [PDF]
This study aimed to investigate the effect of glucose or sucrose as cosubstrate on the kinetics of 4-chlorophenol (4-CP) biodegradation by 4-CP-acclimated activated sludge.
Halim, Nurul Nornazifah Abdul +2 more
core

