Results 61 to 70 of about 173,856,276 (259)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Binding kinetics and affinity for interaction of Saccharomyces cerevisiae mannan with LprG.
, 2014 Binding kinetics and affinity for interaction of Saccharomyces cerevisiae mannan with LprG.
Supriya Shukla (651747) +9 more
core +1 more source
Mathematical model of viral kinetics in vitro estimates the number of E2-CD81 complexes necessary for hepatitis C virus entry. [PDF]
PLoS Computational Biology, 2011 Interaction between the hepatitis C virus (HCV) envelope protein E2 and the host receptor CD81 is essential for HCV entry into target cells. The number of E2-CD81 complexes necessary for HCV entry has remained difficult to estimate experimentally.
Pranesh Padmanabhan, Narendra M Dixit
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Binding kinetics and affinities for interaction of Mtb substrates with LprG and LprG-V91W.
, 2014 Binding kinetics and affinities for interaction of Mtb substrates with LprG and LprG-V91W.
Supriya Shukla (651747) +9 more
core +1 more source
Numerical analysis of phase decomposition in A-B binary alloys using Cahn-Hilliard equations [PDF]
Materials Research, 2013 The analysis of phase decomposition was carried out using the nonlinear and linear Cahn-Hilliard equations in a hypothetical A-B alloy system with a miscibility gap.
Susana Lezama-Alvarez +3 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Frontiers in Pharmacology, 2019 The glycoengineering approach is used to improve biophysical properties of protein-based drugs, but its direct impact on binding affinity and kinetic properties for the glycoengineered protein and its binding partner interaction is unclear.
Saehyung Lee +10 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Tractable RNA–ligand interaction kinetics
, 2017 Background The binding of small ligands to RNA elements can cause substantial changes in the RNA structure. This constitutes an important, fast-acting mechanism of ligand-controlled transcriptional and translational gene regulation implemented by a wide ...
Sebastian Will +2 more
core +1 more source