Results 211 to 220 of about 40,318 (318)

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Probing centromere-kinetochore core complex CENP-L/M assembly using cenpemlin. [PDF]

J Mol Cell Biol
Durojaye OA, Yang F, Gao X, Aikhionbare F, Zhang L, Liu X, Yao X.   +6 more
europepmc   +1 more source

The Spindle Checkpoint of the YeastSaccharomyces cerevisiaeRequires Kinetochore Function and Maps to the CBF3 Domain [PDF]

, 2001
Richard D. Gardner, Atasi Poddar, Chris Yellman, Penny A. Tavormina, M. Cristina Monteagudo, Daniel J. Burke   +5 more
openalex   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Spindle integrity is regulated by a phospho-dependent interaction between the Ndc80 and Dam1 kinetochore complexes. [PDF]

PLoS Genet
Nelson CR, Mallett DR, Biggins S.
europepmc   +1 more source

Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes [PDF]

, 2001
Leana M. Topper, Holger Bastians, Joan Ruderman, Gary J. Gorbsky   +3 more
openalex   +1 more source

Simultaneous editing of SPO11‐1, REC8 and OSD1 yields aneutetraploid soybeans

Plant Biotechnology Journal, EarlyView.
Jing Wang, Kejian Wang, Wei‐Cai Yang, Hong‐Ju Li   +3 more
wiley   +1 more source

Integration of Optical Genome Mapping in the Cytogenomic and Molecular Work‐Up of Hematological Malignancies: Expert Recommendations From the International Consortium for Optical Genome Mapping

American Journal of Hematology, Volume 100, Issue 6, Page 1029-1048, June 2025.
ABSTRACT The latest updates to the classification of hematolymphoid malignancies using the World Health Organization (WHO, 5th ed.) and ICC (International Consensus Classification) criteria highlight the critical need for comprehensive and precise cytogenomic data for diagnosis, prognostication, and treatment.
Rashmi Kanagal‐Shamanna, Anna Puiggros, Isabel Granada, Gordana Raca, Katrina Rack, Mar Mallo, Barbara Dewaele, Adam C. Smith, Yassmine Akkari, Brynn Levy, Robert P. Hasserjian, Adela Cisneros, Marta Salido, Guillermo Garcia‐Manero, Hui Yang, M. Anwar Iqbal, Ravindra Kolhe, Francesc Solé, Blanca Espinet   +18 more
wiley   +1 more source

Single-molecule tracking reveals the dynamic turnover of Ipl1 at the kinetochores in <i>Saccharomyces cerevisiae</i>. [PDF]

Life Sci Alliance
Podh NK, Das A, Kumari A, Garg K, Yadav R, Kashyap K, Islam S, Gupta A, Mehta G.   +8 more
europepmc   +1 more source

Localization of Mad2 to Kinetochores Depends on Microtubule Attachment, Not Tension

, 1998
Jennifer Waters, Rey Huei Chen, Andrew W. Murray, E. D. Salmon   +3 more
openalex   +2 more sources