CRISPR-Cas9 precision editing of kinetochore protein phosphosite codons in <i>Leishmania mexicana</i>. [PDF]
McNiven C +4 more
europepmc +1 more source
Making Two out of One: Kinesin Motors Driving Plant Cell Division
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source
Microtubule depolymerization at kinetochores restricts anaphase spindle elongation. [PDF]
Chen GY +3 more
europepmc +1 more source
ABSTRACT Pollen is a male gametophyte of angiosperms. Following meiosis, the microspore undergoes an asymmetric division called pollen mitosis I (PMI), which produces two cells of different sizes: a large vegetative cell and a small generative cell. Polarized nuclear migration and positioning during PMI are important for successful pollen development ...
Yoko Mizuta +5 more
wiley +1 more source
Microtubules guide Aurora B substrate geometries for accurate chromosome segregation. [PDF]
Niu Y +7 more
europepmc +1 more source
Decoding the Factor H‐Related Proteins: Gatekeepers of Complement Dysregulation in AMD
This review will explore the role of the factor H‐related (FHR) proteins in age‐related macular degeneration (AMD), their accumulation in the outer blood/retinal barrier, and how they may contribute to barrier dysfunction and inflammation. ABSTRACT Age‐related macular degeneration (AMD) is the third most common form of blindness in the Western world ...
Jiaqi Tang +2 more
wiley +1 more source
De novo assembly and single-molecule study of kinetochore-microtubule interactions. [PDF]
Larson JD, Worst LR, Asbury CL.
europepmc +1 more source
Abstract ERCC6L2 disease (ED) is a rare bone marrow failure syndrome caused by biallelic germline mutations in ERCC6L2. ED leads to the accumulation of somatic TP53 mutations, myelodysplastic syndrome, and acute myeloid leukemia (AML) with erythroid predominance and poor prognosis.
Laura Langohr +19 more
wiley +1 more source
Uncovering Prognostic Biomarkers Underlying Hepatocellular Carcinoma Through Integrative Multi-Omics and a Network-Based Approach. [PDF]
Rahmani AH, Beg A, Sarwar T, Khan AA.
europepmc +1 more source
Augmented CENH3 loading is accompanied by transcriptional and epigenetic reprogramming at rice centromeres during meiosis. [PDF]
Cao L +13 more
europepmc +1 more source

