Results 171 to 180 of about 94,326 (306)

Uncovering the Mechanisms that Control Unattached Kinetochore Clustering

Thesis (Ph.D.)--University of Washington, 2025The equal partitioning of the genome during cell division is essential for the survival of an organism. Errors in this process are hallmarks of many human cancers.
Mallett, Darren R
core  

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines. [PDF]

Proc Natl Acad Sci U S A
Zhao G, Sharma A, Tang J, Aleman M, Liang X, Miner L, Qi J, Xiang W, Tian F, Goldberg Y, He Z, Shen K, Peris L, L Schwarz T.   +13 more
europepmc   +1 more source

Immunohistochemistry as a tool for identifying EGFR amplification in CNS tumors

Brain Pathology, Volume 36, Issue 4, July 2026.
EGFR gene amplification constitutes a diagnostic hallmark for glioblastoma, IDH‐wildtype (GB, IDH‐WT). Herein, we demonstrated that EGFR IHC is a highly specific and sensitive biomarker for identifying EGFR amplification and should be part of the neuropathologist's routine panel of antibodies.
Arnault Tauziède‐Espariat, Mary Bah, Farah Sassi, Noémie Pucelle, Charlotte Berthaud, Marion Mandoula, Zeina Dababou, Noah Carnes, Leïla Brissez, Lauren Hasty, Euphrasie Servant, Alice Métais, Pascale Varlet   +12 more
wiley   +1 more source

Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship. [PDF]

Cell Cycle
Pleuger R, Westermann S.
europepmc   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Species Dependent Toxicity Comparison Outcome

Advanced Science, Volume 13, Issue 34, 19 June 2026.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao, Zhan Yu, Sihang Liu, Yuheng Liu, Chong Deng, Yugang Zhao, Yi Huang, Zhi‐Gang Zheng   +7 more
wiley   +1 more source

Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy. [PDF]

Elife
Koch LB, Ghosh T, Spanos C, Marston AL.
europepmc   +1 more source

Revisiting Genetic Relationships of the Endangered Austrian Turopolje With Balkan and Commercial Pig Breeds Using Genome‐Wide SNP Data

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT The endangered Austrian Turopolje (AT) pig population, which originated from six Croatian Turopolje founders imported during the early 1990s, is nowadays preserved through a national conservation project. This study aims to identify genetic relations, genetic distances and migration events between the AT population, four Austrian commercial ...
Marco Santo Cannarella, Johann Sölkner, Silvia Bruno, Elena Ciani, Gábor Mészáros   +4 more
wiley   +1 more source

Proteomics reveals extensive phosphoregulation of outer kinetochore protein KNL1. [PDF]

MicroPubl Biol
Jurasin AC, Frank AR, Biggins S.
europepmc   +1 more source