Results 171 to 180 of about 89,793 (256)

Zfhx3 is required for proper spindle assembly and chromosome segregation during oocyte meiosis I in mice. [PDF]

Front Cell Dev Biol
Huang C, Chang H, Zhao X, Chen S, Wang X, Dong JT.   +5 more
europepmc   +1 more source

CRISPR Screen Reveals Pathways and Factors Driving Tyrosine Kinase Inhibitor Resistance in Hepatocellular Carcinoma

Cancer Medicine, Volume 15, Issue 8, August 2026.
One thousand nine hundred sixty‐two genes associated with HCC TKI treatment responsiveness were identified through an internal unbiased genome‐wide CRISPR/Cas9 screening. A comprehensive HCC TKI treatment response landscape was constructed by integrating 20 datasets comprising a total of 322 TKI‐treated or TKI‐resistant HCC samples.
Si‐Yu Chen, Li‐Hua Yang, Zi‐Qian Liang, Jian‐Di Li, Shi‐de Li, Yu‐Long Deng, Guo‐Qiang Chen, Jing‐Wen Ling, Sheng‐Sheng Zhou, Gang Chen, Rong‐Quan He   +10 more
wiley   +1 more source

Dynamic crotonylation of Bub3 regulates mitotic checkpoint silencing and chromosome segregation. [PDF]

J Mol Cell Biol
Shi X, Yu X, Wang W, Xiong F, Yuan X, Hu Q, Song X, Dou Z, Yao X, Zhang L.   +9 more
europepmc   +1 more source

Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar, Ira Abid, Syeda Eman Fatima, Abdum Muneeb Sandhu, Zain Fatima, Humayun Nasir, Fatima Arshad, Abdul Rehman Shahid Khan, Muhammad Husnain Ahmad, Masab Ali   +9 more
wiley   +1 more source

Finding a role for non-coding DNA in trypanosomes. [PDF]

Elife
Schmidt MR.
europepmc   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Proliferating toward sex: characterization of cell division of <i>Toxoplasma gondii</i>'s pre-sexual stages. [PDF]

mBio
Sena F, Hakimi M-A, Francia ME.
europepmc   +1 more source

Karyotype Variation and Environmental Adaptation in the Invasive Alien Freshwater Flatworm Girardia in China

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Our findings provide a comprehensive baseline of the distribution, reproductive strategies, and environmental adaptations of invasive Girardia species, and underscore the urgent need for continued monitoring and effective management to safeguard native biodiversity.
Lei Wang, Wei‐Min Ren, Xin‐Xin Sun, De‐Zeng Liu, Zi‐Mei Dong, Guang‐Wen Chen   +5 more
wiley   +1 more source

Microtubule end stabilisation by cooperative oligomers of Ska and Ndc80 complexes. [PDF]

EMBO J
Radhakrishnan RM, Stokes L, Day M, Huis In 't Veld PJ, Volkov VA.   +4 more
europepmc   +1 more source

Prenatal Genetic Testing for Beckwith‐Wiedemann Syndrome: Considerations, Challenges and Observations (A Real‐World Study)

Prenatal Diagnosis, Volume 46, Issue 9, Page 1486-1493, August 2026.
ABSTRACT Objective Prenatal genetic testing for imprinting disorders is rarely requested with the exception of Beckwith‐Wiedemann syndrome (BWS) which is associated with specific ultrasound findings (e.g., placental mesenchymal dysplasia, omphalocele). However, genetic testing for BWS is challenging as aberrant DNA methylation has to be addressed which
Melissa Connolly, Louise McClelland, Pierpaola Tannorella, Tanja Richter, Ester Mainini, Andreas Dufke, Annette Lischka, Matthias Begemann, Katja Eggermann, Thomas Eggermann, Silvia Russo   +10 more
wiley   +1 more source