Results 151 to 160 of about 98,180 (299)

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

open access: yesThe FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas   +4 more
wiley   +1 more source

Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate‐resilient apple breeding

open access: yesJournal of Integrative Plant Biology, EarlyView.
This comprehensive map of genetic variation in wild apple (Malus baccata) and set of key genes associated with adaptation to temperature, precipitation, and soil properties establishes a foundation for breeding climate‐resilient apple cultivars and conserving the genetic resources of wild crop relatives.
Ying Su   +30 more
wiley   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

open access: yesJournal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba   +14 more
wiley   +1 more source

ATXR5 and ATXR6 restrict meiotic crossover formation within heterochromatin in Arabidopsis

open access: yesJournal of Integrative Plant Biology, EarlyView.
The Arabidopsis H3K27 mono‐methyltransferases ATXR5 and ATXR6 repress crossovers within meiotic heterochromatin, are required for heterochromatin condensation and H3K27me1 establishment, and specifically influence the maintenance of DNA methylation in meiocytes.
Jun Zhang   +7 more
wiley   +1 more source

Cell cycle dependent methylation of Dam1 contributes to kinetochore integrity and faithful chromosome segregation.

open access: yesPLoS Genetics
The kinetochore, a megadalton structure composed of centromeric (CEN) DNA and protein complexes, is required for faithful chromosome segregation in eukaryotes.
Prashant K Mishra   +11 more
doaj   +1 more source

Recent advances in the genomics of sugarcane (Saccharum)

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang   +5 more
wiley   +1 more source

Beyond single cells: Ten years of commercial lattice light‐sheet microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Lattice light‐sheet microscopy (LLSM) enables gentle, rapid, volumetric fluorescence imaging of living biological systems. The technique employs Bessel beam interference to produce a light‐sheet which retains its thickness over a relatively large field‐of‐view compared to other light‐sheets.
Helena L. E. Coker, David S. Corcoran
wiley   +1 more source

AUXIN RESPONSE FACTORs: from transcription factors to auxin effectors

open access: yesNew Phytologist, EarlyView.
Molecular evolution of AUXIN RESPONSE FACTOR (ARF) effector function. Summary Signalling pathways have originated and diversified extensively during evolution. Using AUXIN RESPONSE FACTORs (ARFs) as a model, we examine how a plant signalling system evolved through the co‐option of pre‐existing transcriptional regulators, a principle well established in
Melissa Dipp‐Álvarez   +1 more
wiley   +1 more source

Selection shapes the evolution of genome size in a globally invasive plant

open access: yesNew Phytologist, EarlyView.
Abundance, genomic distribution and structural characteristics of transposable elements (TEs) and ribosomal RNA (rRNA) genes across the common ragweed (Ambrosia artemisiifolia L.) reference genome. Summary Biological invasions provide powerful natural experiments for understanding how genome architecture responds to novel climatic environments ...
Byonkesh Nongthongbam   +6 more
wiley   +1 more source

Unique Presentation of Metastatic Malignant Germ Cell Tumour Diagnosed on Pleural Effusion Cytology

open access: yes
Cytopathology, EarlyView.
Scarlet Brockmoeller   +3 more
wiley   +1 more source

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