Results 211 to 220 of about 98,180 (299)

STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cervical Adenocarcinoma

Cancer Medicine, Volume 15, Issue 9, September 2026.
STK11 alterations, including mutations, focal deletions, and structural disruption of chromosome 19p, define a distinct molecular subgroup of cervical adenocarcinoma associated with younger age at diagnosis, poorer survival, and reduced benefit from immune checkpoint inhibitors, supporting improved molecular classification and future precision ...
Emma W. Robinson, Elisabeth A. Murphy, Anaseidy Albanez, Sonam Tulsyan, Hong Lou, Yi Xie, Weiyin Zhou, Qian Yang, Tawnjerae Joe, Tongwu Zhang, Jia Liu, Wen Luo, Dongjing Wu, Herbert Higson, Mathias Viard, Mary Carrington, Matthew Oberley, Hesler Morales, Lisa Mirabello, Enrique Alvirez, Roberto Orozco, Eduardo Gharzouzi, Michael Dean   +22 more
wiley   +1 more source

Proteomics reveals extensive phosphoregulation of outer kinetochore protein KNL1. [PDF]

MicroPubl Biol
Jurasin AC, Frank AR, Biggins S.
europepmc   +1 more source

SLE Presenting With Unilateral Loculated Pleural Effusion in a Young Hypertensive Female: A Rare Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Amrit Tripathi, Ujwal Sah, Saurav Shah, Shivaditya Singh, Surya Raj Nishad   +4 more
wiley   +1 more source

Microtubule-dependent regulation of chromatin dynamics by the Smc5/6 complex. [PDF]

iScience
Carré-Simon À, Martuzzi C, Isler S, Batrin R, Pinholt HD, Földes T, Laflamme G, Reguera J, Barbi M, Mirny L, D'Amours D, Fabre E.   +11 more
europepmc   +1 more source

Impact of increased population size and three reference genomes on the development of linkage maps in alfalfa

Crop Science, Volume 66, Issue 5, September/October 2026.
Abstract Alfalfa (Medicago sativa L.) is an important perennial forage crop and a highly heterozygous autotetraploid species (2n = 4x = 32), making high‐density linkage mapping challenging. This study evaluated the effects of reference genome choice and population size on the development of genetic linkage maps using genotyping‐by‐sequencing‐derived ...
Harpreet Kaur, Melinda Dornbusch, Laura M. Shannon, Deborah A. Samac   +3 more
wiley   +1 more source

Outer kinetochore proteins form linear elements to regulate vesicle transport. [PDF]

J Cell Sci
Kowaleski SJ, Bridgewater A, Saraceno C, Dudek M, Pelisch F, Bembenek JN.   +5 more
europepmc   +1 more source

The Rise of Plant Pan‐Genomes: From Genome Variation to Predictive Breeding

Advanced Genetics, Volume 7, Issue 3, September 2026.
Plant pan‐genomics is shifting from genome variation discovery to understanding how diversity drives biological function and breeding value. Future advances will integrate SV/PAV, haplotype diversity, super pan‐genomes, pan‐omics, 3D genomics, and AI to transform genomic resources into predictive breeding strategies.
Dan Peng, Xuezhu Liao, Liang Tang, Zhiqiang Wu   +3 more
wiley   +1 more source

hSpindly dynamics modulate spindle assembly checkpoint signaling, promoting resistance to mitotic inhibitors. [PDF]

iScience
Mora-Santos M, Herrero-Ruiz J, Fennema-Galparsoro D, Belmonte-Fernández A, Ferrandiz N, Romero F.   +5 more
europepmc   +1 more source

Decoding the Heterogeneity of Diffuse Large B‐Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B‐Cell Lymphoma Cell Lines

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Marina Pérez‐Aguilera, Lucía Pedrosa, Sagrario Gómez, Sara Salazar‐Ortego, Ismael Fernández‐Miranda, Rafael Muñoz‐Viana, Paloma Martín‐Acosta, Beatriz L. Martín‐Lunas, Rebeca Jimeno, Natalia Yanguas‐Casás, Beatriz Horcajo, Giovana Roncador, José A. Martínez‐Climent, Ana Ortega‐Molina, Margarita Sánchez‐Beato   +14 more
wiley   +1 more source

A chromatin-associated pool of Aurora A controls kinetochore-microtubule attachments to ensure chromosome biorientation. [PDF]

Sci Adv
Meaders JL, Rodriguez AA, Variyar S, Park S, Cirulli AE, Oegema K, Corbett KD, Desai A.   +7 more
europepmc   +1 more source