Results 221 to 230 of about 91,169 (280)

Nuclear DNA of plastid origin (NUPTs), neglected driver of genome variation and evolutionary innovation

The Plant Journal, Volume 125, Issue 3, February 2026.
Significance Statement Contrary to expectation, NUPTs do not necessarily have a deleterious or ultimately neutral impact, nor are they necessarily purged from the genome. Instead, they can proliferate and eventually become fixed, generating new and novel genes, gene regions and regulatory elements, thereby significantly contributing to plant nuclear ...
Lorenzo Carretero‐Paulet, Juan Pablo Marczuk‐Rojas, Aaron Gálvez‐Salido   +2 more
wiley   +1 more source

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C. [PDF]

Cell Rep
Miao J, Hara M, Su KC, Keys HR, Kong W, Takenoshita Y, Cheeseman IM, Fukagawa T.   +7 more
europepmc   +1 more source

MassIVE MSV000100123 - Proteomics reveals extensive phosphoregulation of outer kinetochore protein KNL1

Biggins, Susan
openalex   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

How Cytoskeletal Disorders Contribute to Errors in the Chromosomal Segregation of Oocytes and Cleavage Stage Embryos. [PDF]

J Dev Biol
Delimitreva S, Chakarova I.
europepmc   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source

DNA damage in mitosis: SOD1 delays anaphase onset. [PDF]

FEBS J
Zachos G.
europepmc   +1 more source

Downregulation of kinetochore-associated 1 gene increases lagging chromosomes and contributes to chromosomal instability in gastric cancer cells. [PDF]

Med Int (Lond)
Ohsaki D, Kanayama K.
europepmc   +1 more source

Construction of protein-based artificial kinetochore in mouse oocytes v1 [PDF]

Yuying Zhou, Kohei Asai, Hirohisa Kyogoku, Tomoya S. Kitajima   +3 more
openalex   +1 more source