Results 241 to 250 of about 40,318 (318)

Exploration of histone protein γ‐H2AX as a prognostic factor in soft tissue sarcomas and its association with biological behavior, immune cell environment and survival in leiomyosarcoma

International Journal of Cancer, Volume 156, Issue 11, Page 2237-2250, 1 June 2025.
What's new? The remarkably poor prognosis of metastasized soft tissue sarcoma (STS) has motivated a search for novel biomarkers and therapeutic approaches. A promising candidate biomarker is H2A histone family member X (H2AX), a key player in DNA damage detection and repair pathways.
Adrian Georg Simon, Su Ir Lyu, Anne Maria Schultheis, David Stahl, Nora Wuerdemann, Sebastian Walter, Lena Hieggelke, Reinhard Buettner, Christiane Josephine Bruns, Peer Eysel, Lars Mortimer Schiffmann, Karl Knipper, Peter Mallmann, Alexander Quaas, Roland Ullrich   +14 more
wiley   +1 more source

The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy. [PDF]

Front Med (Lausanne)
Jin Y, Chen M, Chen F, Gao Z, Li X, Hu L, Cai D, Zhao S, Song Z.   +8 more
europepmc   +1 more source

Centromere/Kinetochore Localization of Human Centromere Protein A (CENP-A) Exogenously Expressed as a Fusion to Green Fluorescent Protein.

, 2000
Kenji Sugimoto, Rika Fukuda, Michio Himeno   +2 more
openalex   +2 more sources

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source

Emerging Roles for Transcription Factors During Mitosis. [PDF]

Cells
Flashner S, Azizkhan-Clifford J.
europepmc   +1 more source

From nuclear pore to kinetochore [PDF]

, 2001
William A. Wells
openalex   +1 more source

Exploration of Neurodegenerative Diseases Using Long‐Read Sequencing and Optical Genome Mapping Technologies

Movement Disorders, Volume 40, Issue 6, Page 996-1008, June 2025.
Abstract Genetic factors play a central role in neurodegenerative disorders. Over the past few decades, significant progress has been made in identifying the causative genes of numerous monogenic disorders, largely due to the widespread adoption of next‐generation sequencing (NGS) technologies in both research and clinical settings.
Guillaume Cogan, Kensuke Daida, Cornelis Blauwendraat, Kimberley Billingsley, Alexis Brice   +4 more
wiley   +1 more source

The kinetochore-associated microtubule motor CENP-E is an essential component for establishing tension at kinetochores in gastric carcinoma cells

, 2000
Xuebiao Yao, T.S. Ravikumar
openalex   +1 more source

Essential Roles of Drosophila Inner Centromere Protein (Incenp) and Aurora B in Histone H3 Phosphorylation, Metaphase Chromosome Alignment, Kinetochore Disjunction, and Chromosome Segregation [PDF]

, 2001
Richard R. Adams, Hélder Maiato, William C. Earnshaw, Mar Carmena   +3 more
openalex   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source