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Plant, Cell &Environment, Volume 49, Issue 6, Page 3151-3154, June 2026.
Ji Hoon Rhee +4 more
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Trends in Plant Science, 2000
Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement. Kinetochores also function in the spindle checkpoint; a surveillance mechanism that ensures that metaphase is complete before anaphase begins.
Hong-Guo Yu +2 more
exaly +3 more sources
Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement. Kinetochores also function in the spindle checkpoint; a surveillance mechanism that ensures that metaphase is complete before anaphase begins.
Hong-Guo Yu +2 more
exaly +3 more sources
Journal of Cell Science, 2023
ABSTRACT The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as long-range organelle transport in neuronal axons and spindle assembly in dividing cells.
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ABSTRACT The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as long-range organelle transport in neuronal axons and spindle assembly in dividing cells.
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The kinetochore of the hemiptera
Chromosoma, 1961(1) Breakage of chromosomes was induced by X-rays in adult and nymphal males of Euschistus servus, E. tristigmus and Solubea pugnax (Pentatomidae; Hemiptera-Heteroptera). (2) The diffuse nature of the kinetochore is demonstrated by the ability of chromosome fragments to perpetuate themselves mitotically through many cell generations of ...
S, HUGHES-SCHRADER, F, SCHRADER
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Biochemical Society Transactions, 2006
The Ran GTPase controls many cellular functions, including nucleocytoplasmic trafficking, spindle assembly, nuclear assembly and cell-cycle progression. Considerable evidence suggests that diffusible Ran-GTP near mitotic chromatin facilitates the release of critical factors from nuclear transport receptors, thereby promoting organization of mitotic ...
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The Ran GTPase controls many cellular functions, including nucleocytoplasmic trafficking, spindle assembly, nuclear assembly and cell-cycle progression. Considerable evidence suggests that diffusible Ran-GTP near mitotic chromatin facilitates the release of critical factors from nuclear transport receptors, thereby promoting organization of mitotic ...
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Centromeres and kinetochores of Brassicaceae
Chromosome Research, 2014The centromere-the primary constriction of monocentric chromosomes-is essential for correct segregation of chromosomes during mitosis and meiosis. Centromeric DNA varies between different organisms in sequence composition and extension. The main components of centromeric and pericentromeric DNA of Brassicaceae species are centromeric satellite repeats.
Inna, Lermontova +2 more
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Centromere and kinetochore structure
Current Biology, 1992Recent studies have begun to yield some insight into the structural and regulatory components of centromeres, and new assays have been developed that promise to be of use in advancing our understanding of centromere structure and function. In the budding yeast Saccharomyces cerevisiae new proteins that are required for centromere function have been ...
W C, Earnshaw, J E, Tomkiel
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The structure of a primitive kinetochore
Trends in Biochemical Sciences, 1989The isolation of yeast centromeres has provided the opportunity to describe the molecular structure of chromosome attachments to the mitotic spindle. Nucleolytic probes of chromatin structure and construction of conditional mutants in centromere function have been used to study the regulation and assembly of centromeres throughout the cell cycle in ...
K, Bloom, A, Hill, M, Kenna, M, Saunders
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The kinetochores of Caenorhabditis elegans
Chromosoma, 1982Light microscopy of the mitotic chromosomes of Caenorhabditis elegans suggests that non-localized kinetochores are present, since the chromosomes appear as stiff rods 1 to 2 micrometers in length and lack any visible constriction. The holokinetic structure was confirmed by reconstructions of electron micrographs of dividing nuclei in serially sectioned
D G, Albertson, J N, Thomson
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