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Kinetochore structure and function

Trends in Cell Biology, 2005
The vertebrate kinetochore is a complex structure that specifies the attachments between the chromosomes and microtubules of the spindle and is thus essential for accurate chromosome segregation. Kinetochores are assembled on centromeric chromatin through complex pathways that are coordinated with the cell cycle.
Gordon K, Chan   +2 more
openaire   +2 more sources

Structure of the mammalian kinetochore

Chromosoma, 1981
The structure of the mammalian trilaminar kinetochore was investigated using stereo electron microscopy of chromosomes in hypotonic solutions which unraveled the chromosome but maintained microtubules. Mouse and Chinese hamster ovary cells were arrested in Colcemid and allowed to reform microtubules after Colcemid was removed. Recovered cells were then
H, Ris, P L, Witt
openaire   +2 more sources

The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber

1982
Publisher Summary Advances in the understanding of the formation, structure, and chemistry of the mammalian kinetochore and its associated fiber are summarized in the chapter. The initiation of chromosome movement during cell division can be correlated with the formation of a fiber, composed primarily of microtubules (MTs) and associated proteins ...
openaire   +2 more sources

Evolving Centromeres and Kinetochores

2017
The genetic material, contained on chromosomes, is often described as the "blueprint for life." During nuclear division, the chromosomes are pulled into each of the two daughter nuclei by the coordination of spindle microtubules, kinetochores, centromeres, and chromatin.
Steven, Friedman, Michael, Freitag
openaire   +2 more sources

BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis

Molecular Cell, 2021
Priyanka Singh   +2 more
exaly  

An updated view of the kinetochore architecture

Trends in Genetics, 2023
Mariko Ariyoshi, Tatsuo Fukagawa
exaly  

Kinetochore

2001
M.A. Hultén, C. Tease
openaire   +1 more source

Dynamics of kinetochore structure and its regulations during mitotic progression

Cellular and Molecular Life Sciences, 2020
Masatoshi Hara   +2 more
exaly  

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