Results 71 to 80 of about 16,601 (180)
Terrestrial animals must conserve water and NaCl to survive dry environments. The kidney reabsorbs 95% of the sodium filtered from the glomeruli before sodium reaches the distal connecting tubules. Excess sodium intake requires the renal kallikrein-kinin
Masataka Majima, Makoto Katori
doaj +1 more source
Objectives: The objectives were to determine if the skin secretion of the European yellow-bellied toad (Bombina variegata), in common with other related species, contains a bradykinin inhibitor peptide and to isolate and structurally characterize this ...
Mu Yang +7 more
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Structural requirements for the procoagulant activity of nucleic acids.
Nucleic acids, especially extracellular RNA, are exposed following tissue- or vessel damage and have previously been shown to activate the intrinsic blood coagulation pathway in vitro and in vivo.
Julia Gansler +6 more
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Changes in the proteomic profile of blood serum in coronary atherosclerosis [PDF]
Background: Our aim was to study changes in the serum proteomic profile in coronary atherosclerosis. Methods: The study involved two groups of patients: 1) men with coronary heart disease and coronary atherosclerosis (n = 15); 2) control (n = 15): men ...
Stakhneva Ekaterina M. +6 more
doaj
The generation of bradykinin (BK; Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) in blood and kallidin (Lys-BK) in tissues by the action of the kallikrein-kinin system has received little attention in non-mammalian vertebrates.
B.C. Prezoto +5 more
doaj +1 more source
Objectives: This study aims to examine the following functional polymorphisms in rheumatoid arthritis (RA) susceptibility: (i) the 587C>T of kininogen gene, (ii) the 287 bp Alu repeat insertion of angiotensin converting enzyme gene, (iii) the 9 bp ...
Anthoula CHATZIKYRIAKIDOU +2 more
doaj
Inhibiting ADORA1 enhances glioma apoptosis and increases its sensitivity to anti-PD1 therapy
IntroductionGlioma, the primary cancerous tumor of the central nervous system in adults, has a poor outlook. Immune checkpoint blockade therapy has exhibited notable efficacy against various cancer types.
Hong-jiang Li +9 more
doaj +1 more source
Phosphorylation is the most commonly studied protein post-translational modification (PTM) in biological systems due to its importance in controlling cell division, survival, growth, etc.
Asier Galán +5 more
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