Results 191 to 200 of about 2,276,672 (229)

KCNJ10 (Kir4.1) potassium channel knockout abolishes endocochlear potential

American Journal of Physiology-Cell Physiology, 2002
Stria vascularis of the cochlea generates the endocochlear potential and secretes K+. K+ is the main charge carrier and the endocochlear potential the main driving force for the sensory transduction that leads to hearing. Stria vascularis consists of two barriers, marginal cells that secrete potassium and basal cells that are coupled via gap junctions
Daniel C, Marcus, Tao, Wu, Philine, Wangemann, Paulo, Kofuji   +3 more
openaire   +2 more sources

Dysfunction of astrocytic Kir4.1 channels induces BDNF expression

Journal of the Neurological Sciences, 2017
M. Kinboshi, T. Mukai, Y. Nagao, S. Shimizu, H. Ito, A. Ikeda, Y. Ohno   +6 more
openaire   +2 more sources

Computational Model for Cross-Depolarization in DRG Neurons via Satellite Glial Cells using [K]o: Role of Kir4.1 Channels and Extracellular Leakage

Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2019
Satellite glial cells (SGCs) are glial cells found in the peripheral nervous system where they tightly envelop the somata of the primary sensory neurons such as dorsal root ganglion (DRG) neurons and nodose ganglion (NG) neurons.
Darshan Mandge, Pooja Shukla, Archita Bhatnagar, R. Manchanda   +3 more
semanticscholar   +1 more source

Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na+ Channel (ENaC)

HYPERTENSION, 2023
BACKGROUND: Kir4.2 and Kir4.1 play a role in regulating membrane transport in the proximal tubule (PT) and in the distal-convoluted-tubule (DCT), respectively.
Xin-Peng Duan, Yu Xiao, X. Su, Jun-Ya Zheng, Susan B Gurley, Jacqueline M. Emathinger, Chao‐ling Yang, James A. McCormick, David H. Ellison, Daohong Lin, Wen‐Hui Wang   +10 more
semanticscholar   +1 more source

Potassium channel KIR4.1-specific antibodies in children with acquired demyelinating CNS disease

Neurology, 2014
A serum antibody against the inward rectifying potassium channel KIR4.1 (KIR4.1-IgG) was recently discovered, which is found in almost half of adult patients with multiple sclerosis. We investigated the prevalence of KIR4.1-IgG in children with acquired demyelinating disease (ADD) of the CNS.
Kraus, V., Srivastava, R., Kalluri, S. R., Seidel, U., Schuelke, M., Schimmel, Mareike, Rostasy, K., Leiz, S., Hosie, S., Grummel, V., Hemmer, B.   +10 more
openaire   +3 more sources

Kir4.1 channel- A universal target in ALS glia

2022
Mitrečić D, Petravić D, editors. Abstracts: International Conference on Neurological Disorders and Neurorestoration; 2022 May 19-22; Dubrovnik, Croatia. Zagreb: Department of Neurology, University Hospital Centre Zagreb: 2022. p. 13. (Neurologia Croatica; Vol. 71; Suppl. 2).
Anđus, Pavle, Perić, Mina, Nikolić, Ljiljana, Bataveljić, Danijela   +3 more
openaire   +1 more source

Increased expression KIR4.1 potassium channel in experimental models of demyelination

Journal of Neuroimmunology, 2014
Histopathological studies confirm the prominent deposition of immunoglobulins (Ig) and the complement activation in acute demyelinating lesions of multiple sclerosis (MS) patients, suggesting that, at least in a subgroup of MS patients, autoantibodies could contribute to the disease.
Laura Turati, Chiara Cordiglieri, Chiara Toscani, Francesca Andreetta, Pia Bernasconi, Renato Mantegazza, Fulvio Baggi   +6 more
openaire   +1 more source

Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons

Molecular Neurobiology, 2023
T. Fujimoto, Kirsten Stam, T. Yaoi, Kenta Nakano, Tetsuya Arai, T. Okamura, K. Itoh   +6 more
semanticscholar   +1 more source

Inward rectifying Kir4.1 channels regulate oligodendrocyte precursor cell differentiation and CNS myelination in vivo

Neuroscience Letters, 2023
Jia-yu Liu, Liang Zhou, Y. Shen
semanticscholar   +1 more source

Prenatal expression of inwardly rectifying potassium channel mRNA (Kir4.1) in rat brain

NeuroReport, 1998
The levels and cellular localization of the mRNA encoding the inwardly rectifying potassium ion channel Kir4.1 were investigated in the embryonic rat brain by Northern blots and in situ hybridization. This transcript was absent at embryonic day 13 (E13), whereas it was clearly present in E14-15 preparations, principally in the neuroepithelium of the ...
W, Ma, L, Zhang, G, Xing, Z, Hu, K H, Iwasa, J R, Clay   +5 more
openaire   +2 more sources