Results 201 to 210 of about 2,276,672 (229)

Heterozygous KCNJ10 Variants Affecting Kir4.1 Channel Cause Paroxysmal Kinesigenic Dyskinesia

Movement Disorders
AbstractBackgroundMore than 60% of paroxysmal kinesigenic dyskinesia (PKD) cases are of uncertain variants.ObjectiveThe aim was to elucidate novel genetic contribution to PKD.MethodsA total of 476 probands with uncertain genetic causes were enrolled for whole‐exome sequencing.
Xiaojun Huang, Xin Fu, Jingying Wu, Xin Cheng, Xiaoqi Hong, Ziyi Li, Lan Zheng, Qing Liu, Shendi Chen, Beisha Tang, Yuwu Zhao, Xiaorong Liu, Xunhua Li, Xiaoli Liu, Zaiwei Zhou, Li Wu, Kan Fang, Ping Zhong, Mei Zhang, Xinghua Luan, Wotu Tian, Xiaoping Tong, Li Cao   +22 more
openaire   +2 more sources

Astrocytic Kir4.1 ion channel deficit drives persistent inflammatory facial pain in males

Brain
Abstract Chronic facial pain, a frequent and disabling condition, is maintained by central sensitization, which results in pain hypersensitivity. Although it is well established that reactive astrocytes play a key role in persistent pain mechanisms, the role of disruption of the normal capacity of astrocytes to maintain neuronal ...
Mountadem, Sarah, Hérault, Karine, Peirs, Cedric, da Silva Borges, Gisela, Voisin, Daniel, Antri, Myriam, Dallel, Radhouane   +6 more
openaire   +2 more sources

Artificial channels for confined mass transport at the sub-nanometre scale

Nature Reviews Materials, 2021
Jie Shen, Gong-Ping Liu, Yu Han
exaly  

Unveiling Ketamine's Influence on Astrocytic Kir4.1 Channels Through Multimodal Analysis: Confocal Microscopy, Immunocytochemistry, Fluorescence Analysis, and Electrophysiology.

Methods in molecular biology
Samo Pirnat, Katja Fink, M. Stenovec, M. Kreft, R. Zorec   +4 more
semanticscholar   +1 more source

Water in Nanopores and Biological Channels: A Molecular Simulation Perspective

Chemical Reviews, 2020
Charlotte I Lynch, Shanlin Rao, Mark S P Sansom   +2 more
exaly  

Discoveries in structure and physiology of mechanically activated ion channels

Nature, 2020
Andrew B Ward, Ardem Patapoutian
exaly  

Astroglial NMDA receptors inhibit expression of Kir4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure

Neurochemistry International, 2015
Marta Obara-Michlewska, Joanna A. Ruszkiewicz, M. Zielińska, A. Verkhratsky, J. Albrecht   +4 more
semanticscholar   +1 more source

Potassium channel KIR4.1 clue to multiple sclerosis

Springer Healthcare News, 2012
openaire   +1 more source

Piezos thrive under pressure: mechanically activated ion channels in health and disease

Nature Reviews Molecular Cell Biology, 2017
Swetha E Murthy, Adrienne E Dubin, Ardem Patapoutian   +2 more
exaly  

VRACs and other ion channels and transporters in the regulation of cell volume and beyond

Nature Reviews Molecular Cell Biology, 2016
Thomas J Jentsch
exaly