Results 51 to 60 of about 21,456 (303)
Exploring the Role of Kisspeptin in Polycystic Ovary Syndrome and Its Associated Pregnancy Complications. [PDF]
Obes RevABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Zhang S +5 more
europepmc +2 more sources
Expression of Kisspeptin 1 in the Brain of the Adult Sea Lamprey Petromyzon marinus
Life, 2021 Kisspeptin peptides play major roles in the regulation of reproduction and puberty onset in mammals. While most mammals only have one kisspeptin gene, other jawed vertebrates present two or three genes. Recent data also revealed the presence of two genes
Daniel Sobrido-Cameán +4 more
doaj +1 more source
Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
, 2016 Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source
The Role of Kisspeptin in the Pathogenesis of Pregnancy Complications: A Narrative Review
International Journal of Molecular Sciences, 2022 Kisspeptins are the family of neuropeptide products of the KISS-1 gene that exert the biological action by binding with the G-protein coupled receptor 54 (GPR54), also known as the KISS-1 receptor.
Magdalena Szydełko-Gorzkowicz +4 more
semanticscholar +1 more source
Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]
, 2015 cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica +3 more
core +1 more source
Genes, 2022 The hypothalamus–pituitary–testis axis controls the production of spermatozoa, and the kisspeptin system, comprising Kiss1 and Kiss1 receptor (Kiss1R), is the main central gatekeeper.
Elena Mele +8 more
semanticscholar +1 more source
Quantification of rat kisspeptin using a novel radioimmunoassay.
PLoS ONE, 2014 Kisspeptin is a hypothalamic peptide hormone that plays a pivotal role in pubertal onset and reproductive function. Previous studies have examined hypothalamic kisspeptin mRNA expression, either through in situ hybridisation or real-time RT-PCR, as a ...
James S Kinsey-Jones +6 more
doaj +1 more source
Frontiers in Veterinary Science, 2018 Kisspeptin is a neuropeptide that governs the reproductive axis upstream to GnRH. We wanted to study whether kisspeptin modulates plasma LH and FSH levels and ovarian follicular dynamics in buffaloes and whether kisspeptin can be used for fixed time ...
Vishalkumar Pottapenjera +8 more
doaj +1 more source
The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats. [PDF]
, 2016 Reproductive senescence, the point in time when females cease to show estrous cyclicity, is associated with endocrine changes in the hypothalamus, pituitary, and gonads. However, the mechanisms triggering this transition are not well understood.
Bentley, George E +4 more
core +1 more source
Acute Effects of Kisspeptin Administration on Bone Metabolism in Healthy Men
Journal of Clinical Endocrinology and Metabolism, 2022 Context Osteoporosis results from disturbances in bone formation and resorption. Recent nonhuman data suggest that the reproductive hormone kisspeptin directly stimulates osteoblast differentiation in vitro and thus could have clinical therapeutic ...
A. Comninos +14 more
semanticscholar +1 more source