Biological Significance of Kisspeptin–Kiss 1 Receptor Signaling in the Habenula of Teleost Species
Frontiers in Endocrinology, 2018 Kisspeptin is a neuropeptide, encoded by kisspeptin 1 (KISS1)/Kiss1 gene, which primarily acts as the regulator of reproductive functions via its receptor, kisspeptin receptor (KissR) in vertebrates.
Satoshi Ogawa, Ishwar S. Parhar
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Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells [PDF]
, 2013 Reproduction is integrated by interaction of neural and hormonal signals converging on hypothalamic neurons for controlling gonadotropin-releasing hormone (GnRH).
Glidewell-Kenney, Christine +9 more
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Frontiers in EndocrinologyBackgroundKisspeptin has been indicated to be a biomarker of fetal growth. Although some evidence suggested that maternal kisspeptin concentrations in early pregnancy were associated with increased fetal growth, studies are still limited and the effect ...
Jiaxian Chen +8 more
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Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]
, 2012 Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Bloom, Stephen R. +11 more
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Kisspeptin Regulation of Arcuate Neuron Excitability in Kisspeptin Receptor Knockout Mice [PDF]
Endocrinology, 2015 The G protein-coupled receptor 54 (GPR54) is critical for kisspeptin to activate GnRH neurons to modulate fertility. However, the often mismatching distribution of kisspeptin and GPR54 in the brain suggests that kisspeptin may also act on other receptors.
Xinhuai, Liu, Allan, Herbison
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Gynecological Endocrinology, 2023 Introduction The purpose of this study was to determine the association between kisspeptin levels and obesity in patients with polycystic ovary syndrome (PCOS) or in healthy controls and to explore the correlation between levels of kisspeptin and various
Meixiu Gao +5 more
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Lower circulating kisspeptin and primary hypogonadism in men with type 2 diabetes
Endocrinology, Diabetes & Metabolism, 2019 Introduction Kisspeptin influence on male androgens is partially understood. We aimed to evaluate serum concentrations of kisspeptin among Ghanaian men with type 2 diabetes and to identify related factors that may contribute to altering circulating ...
Henry Asare‐Anane +6 more
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Effect of Peripheral Administration of Kisspeptin-10 on Dynamic LH Secretion in Prepubertal Ewes [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 The aim of the present study was to clarify the effect of kisspeptin-10 on LH secretion in prepubertal ewes. In experiment 1, prepubertal ewes fitted with indwelling jugular catheters were randomly assigned to receive 0, 0.5, 1 or 2 mg of kisspeptin-10 ...
Jun Wang +4 more
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Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
, 2013 Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
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Morphine Attenuates Testosterone Response to Central Injection of Kisspeptin in Male Rats [PDF]
International Journal of Fertility and Sterility, 2014 Background Kisspeptin and naloxone stimulate the reproductive axis while morphine inhibits its function. We have investigated the effect of central injection of kisspeptin-10 on mean plasma testosterone concentration in morphine or naloxone pretreated
Fariba Mahmoudi +2 more
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