Results 71 to 80 of about 16,602 (265)

Factors Associated With Non‐Vasomotor Menopause Symptoms Experienced by 7285 Women: A UK‐Wide National Survey

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate the factors associated with non‐vasomotor menopause symptoms among women in the UK, focusing on the perceived importance of specific symptoms and their association with demographic and treatment‐related factors. Design A cross‐sectional online survey.
Rhianna Davies, Ashwin Goyal, Zachary Nash, Sarah Hillman, Melanie Davies, Nick Panay, Jane Daniels, Tim Hillard, Bonnie Grant, Paula Briggs, Lynne Robinson, Haitham Hamoda, Channa N. Jayasena   +12 more
wiley   +1 more source

Regulation and Possible Functions of Kisspeptin in the Medial Amygdala

Frontiers in Endocrinology, 2017
Kisspeptin, encoded by the Kiss1 gene, is required for reproduction. Humans and mice lacking kisspeptin or its receptor, Kiss1r, have impairments in reproductive physiology and fertility.
Shannon B. Z. Stephens, Alexander S. Kauffman   +1 more
doaj   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

A male‐dominant cell group expressing calbindin‐D28K and androgen receptor in the mouse preoptic area requires postnatal testicular androgens and histone deacetylation

Journal of Neuroendocrinology, EarlyView.
Abstract The mouse brain is masculinized by postnatal testicular androgens, which are active after conversion to estrogens and modulate gene expression epigenetically, at least in part. The preoptic area contains a sexually dimorphic nucleus (SDN) comprising calbindin D‐28K (Calb) neurons with a male‐biased sex difference in cell number (Calb‐SDN ...
Yusa Arai, Shinji Tsukahara
wiley   +1 more source

The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons. [PDF]

, 2013
Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide.
Chilumuri, A., Chilumuri, A., Milton, N.G.N., Milton, N.G.N.   +3 more
core   +14 more sources

Kisspeptin and Endometriosis-Is There a Link? [PDF]

J Clin Med
This article presents a narrative review that explores the potential link between kisspeptin—a key regulator of the hypothalamic-pituitary-gonadal axis—and the pathogenesis of endometriosis. Kisspeptin plays a significant role in regulating reproductive functions by modulating the release of gonadotropin-releasing hormone (GnRH), which in turn ...
Meczekalski B, Nowicka A, Bochynska S, Szczesnowicz A, Bala G, Szeliga A.   +5 more
europepmc   +3 more sources

Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction

Journal of Neuroendocrinology, EarlyView.
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
Naira da Silva Mansano, Calvin Vinh Lieu, Alfonso Abizaid   +2 more
wiley   +1 more source

Evidence That Agouti-Related Peptide May Directly Regulate Kisspeptin Neurons in Male Sheep

Metabolites, 2021
Agouti-related peptide (AgRP) neurons, which relay information from peripheral metabolic signals, may constitute a key central regulator of reproduction.
Christina M. Merkley, Sydney L. Shuping, Jeffrey R. Sommer, Casey C Nestor   +3 more
doaj   +1 more source

Kisspeptin and Puberty in Mammals [PDF]

, 2013
Since the discovery of the G-protein coupled receptor 54 (kisspeptin receptor) and its ligand, kisspeptin, our understanding of the neurobiological mechanisms that govern the pituitary-gonadal axis has evolved dramatically. In this chapter, we have reviewed progress regarding the relationship between kisspeptin and puberty, and have proposed a novel ...
Tony M. Plant, Kathryn A. Guerriero, Ei Terasawa   +2 more
openaire   +3 more sources

Exploring the Role of Kisspeptin in Polycystic Ovary Syndrome and Its Associated Pregnancy Complications

Obesity Reviews, EarlyView.
ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang, Xinmeng Sun, Haiyun Guan, Rongmin Wang, Wei Zhang, Hexia Xia   +5 more
wiley   +1 more source