Results 71 to 80 of about 21,456 (303)
Kisspeptin and seasonality in sheep [PDF]
Peptides, 2009 Sheep are seasonal breeders, experiencing a period of reproductive quiescence during spring and early summer. During the non-breeding period, kisspeptin expression in the arcuate nucleus is markedly reduced. This strongly suggests that the mechanisms that control seasonal changes in reproductive function involve kisspeptin neurons.
Clarke, I.J. +4 more
openaire +3 more sources
Biological Significance of Kisspeptin–Kiss 1 Receptor Signaling in the Habenula of Teleost Species
Frontiers in Endocrinology, 2018 Kisspeptin is a neuropeptide, encoded by kisspeptin 1 (KISS1)/Kiss1 gene, which primarily acts as the regulator of reproductive functions via its receptor, kisspeptin receptor (KissR) in vertebrates.
Satoshi Ogawa, Ishwar S. Parhar
doaj +1 more source
Kisspeptin and Testicular Function—Is It Necessary? [PDF]
International Journal of Molecular Sciences, 2020 The role of kisspeptin in stimulating hypothalamic GnRH is undisputed. However, the role of kisspeptin signaling in testicular function is less clear. The testes are essential for male reproduction through their functions of spermatogenesis and steroidogenesis.
Aditi Sharma +4 more
openaire +4 more sources
Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells [PDF]
, 2013 Reproduction is integrated by interaction of neural and hormonal signals converging on hypothalamic neurons for controlling gonadotropin-releasing hormone (GnRH).
Glidewell-Kenney, Christine +9 more
core +1 more source
Kisspeptin is Testosterone independent regulator of Sexual Motivation in Male Rats
Journal of Experimental Biology and Agricultural Sciences, 2022 Kisspeptin is the peptide product of the KISS-1 gene and endogenous agonist for the Kiss1 receptor. It is well known that kisspeptin acts centrally, and stimulates the secretion of gonadoliberin (GnRH).
L. Magarramova +5 more
semanticscholar +1 more source
Pacemaking kisspeptin neurons [PDF]
Experimental Physiology, 2013 New findings What is the topic for this review?This review focuses on analysis of the electrophysiological properties of hypothalamic kisspeptin neurons. What advances does it highlight?Molecular and cellular electrophysiological analysis of kisspeptin neurons reveals that they express the critical pacemaker channels for generating burst‐firing ...
Martin J, Kelly +3 more
openaire +2 more sources
Frontiers in EndocrinologyBackgroundKisspeptin has been indicated to be a biomarker of fetal growth. Although some evidence suggested that maternal kisspeptin concentrations in early pregnancy were associated with increased fetal growth, studies are still limited and the effect ...
Jiaxian Chen +8 more
doaj +1 more source
Kisspeptin: Beyond the Brain [PDF]
Endocrinology, 2015 The hypothalamic-based kisspeptin-signaling system is a major positive regulator of the neuroendocrine-reproductive axis in mammals. During the last decade, major advances have been made in understanding how this signaling system is regulated and how it can be manipulated clinically to achieve beneficial outcomes in treating sex steroid-dependent ...
Moshmi, Bhattacharya, Andy V, Babwah
openaire +2 more sources
Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]
, 2012 Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Bloom, Stephen R. +11 more
core +1 more source
International Journal of Molecular Sciences, 2021 Estrogen produced by ovarian follicles plays a key role in the central mechanisms controlling reproduction via regulation of gonadotropin-releasing hormone (GnRH) release by its negative and positive feedback actions in female mammals.
Y. Uenoyama +3 more
semanticscholar +1 more source