Results 41 to 50 of about 5,771 (170)

Light‐Controlled Exposure of Cancer Cells to Reactive Oxygen Species Using Organic Semiconductor Thin Films

Advanced Materials Interfaces, EarlyView.
Spin‐coated films of the conjugated polymer F8T2 (poly (9,9‐dioctylfluorene‐alt‐bithiophene)) generate superoxide at the film‐medium interface, enabling precise delivery of reactive oxygen species (ROS) as visible‐light “ROS patches.” Coated surfaces drive rapid, localised cytotoxicity in MCF7 cancer monolayers under white light, providing a reagent ...
Joe Kaye, Niculina Miron, Benjamin Fortes Mayer, Yukai Shi, Boyuan Chen, Lewis Krzeczkowski, Robert J. E. Westbrook, Saif A. Haque, Ali Salehi‐Reyhani   +8 more
wiley   +1 more source

Pulsed DC Sputter Deposition of Stable Turbostratic Boron Nitride Thin Films

Advanced Materials Interfaces, EarlyView.
Boron nitride (BN) films are deposited by sputtering from a boron target. During deposition, a substrate bias voltage is applied between the plasma and the sample, which reduces excess boron in the film and enhances the crystallinity. This process prevents the formation of boric acid and ammonium borate hydrate.
Josef Schätz, Michael Krenzer, Tim Schaffus, Martin Otto, Fabian Kühnel, Fabian Streb, Günther Benstetter, Georg S. Duesberg, Stephan Pindl, Max C. Lemme   +9 more
wiley   +1 more source

Ubiquitous protein lactylation in health and diseases

Cellular & Molecular Biology Letters
For decades, lactate has been considered a byproduct of glycolysis. The lactate shuttle hypothesis shifted the lactate paradigm, demonstrating that lactate not only plays important roles in cellular metabolism but also cellular communications, which can ...
Junyong Wang, Ziyi Wang, Qixu Wang, Xiao Li, Yaping Guo   +4 more
doaj   +1 more source

Influence of rotating magnetic field on gas-liquid volumetric mass transfer coefficient

Chemical and Process Engineering, 2017
The main objective of these experiments was to study the oxygen mass transfer rate through the volumetric mass transfer coefficient (kLa) for an experimental set-up equipped with a rotating magnetic field (RMF) generator and various liquids.
Rakoczy Rafał, Konopacki Maciej, Kordas Marian, Drozd Radosław, Fijałkowski Karol   +4 more
doaj   +1 more source

Degradable Donor‐Acceptor Polymeric Mixed Ionic‐Electronic Conductors for Transient Electronics

Advanced Materials Technologies, EarlyView.
Here, we report degradable donor–acceptor (D–A) polymeric mixed ionic‐electronic conductors for transient electronics. We take a systematic side chain engineering approach to elucidate how molecular‐level modifications of donor–acceptor (D–A) polymer structures can satisfy demands that are often conflicting: degradability, charge carrier transport, and
Angela Lin, Zhichang Liu, Saroj Upreti, Stanley Lo, Nathan Sung Yuan Hsu, Xiaodan Gu, Sihong Wang, Helen Tran   +7 more
wiley   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration

Advanced Science, EarlyView.
A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang, Jing Wang, Xinyi Li, Bo Yu, Yiduo Chen, Yirong Guo, Honglin Qian, Meng Hu, Haoyang Liu, Wenhui Liu, Han Xu, Kefeng Ren, M. Cristina L. Martins, Jian Ji   +13 more
wiley   +1 more source

İki kardeşte gözlenen konjenital lober amfizem

Sakarya Tıp Dergisi, 2012
Konjenital lober amfizem (KLA) genellikle bir lobda hiperinflasyonla karakterizedir. Sol üst lob (%50) ve sağ orta lob (%30) en sık etkilenmekte olup bunu sağ üst lob izlemektedir. Literatürde aile öyküsü ile KLA arasında bir ilişkiden bahsedilmemektedir.
Atila Türkyılmaz, Atilla Eroğlu, Aysel Kurt, Niyazi Diri, Yener Aydın   +4 more
doaj   +1 more source

Bevlogen door de klas

VELON : tijdschrift voor lerarenopleiders, 2006
Wat zorgt ervoor dat een leraar plezier in het werk heeft en met enthousiasme naar het werk gaat? Dit artikel gaat over de factoren die er toe bijdragen dat een leraar bevlogen raakt, en welke gevolgen dit kan hebben. Het begrip bevlogenheid wordt nader toegelicht, en geplaatst in het JD-R model, een model dat de relatie tussen onder andere ...
Matthijs Bal, Arnold Bakker, T. Kallenberg   +2 more
openaire   +1 more source

UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer

Advanced Science, EarlyView.
This study integrates multi‐omics to reveal the critical role of UBE2T in driving malignancy and stromal co‐evolution in PDAC. UBE2T potentiates glycolysis by regulating p53 degradation via a positive feedback loop, thereby promoting histone H3 lysine 18 lactylation in CAFs and stromal deposition. The UBE2T inhibitor PGG represents a potential strategy
Yong Ma, Wenbo Liu, Mingdou Li, Tao Wang, Bin Zhao, Keshen Wang, Qichen He, Haonan Sun, Huiguo Qing, Xiaoying Guan, Wengui Shi, Long Qin, Yuman Dong, Huinian Zhou, Zeyuan Yu, Xiangyan Jiang, Zuoyi Jiao   +16 more
wiley   +1 more source