Results 51 to 60 of about 12,544 (218)
Kaposiform lymphangiomatosis effectively treated with MEK inhibition
EMBO Molecular Medicine, 2020 Kaposiform lymphangiomatosis (KLA) is a rare lymphatic anomaly primarily affecting the mediastinum with high mortality rate. We present a patient with KLA and significant disease burden harboring a somatic point mutation in the Casitas B lineage lymphoma
Jessica B Foster +6 more
doaj +1 more source
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Estudo da produção de inulinase por Kluyveromyces marxianus ATCC 36907 [PDF]
, 1996 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoA produção de inulinase por Kluyveromyces marxianus ATCC 36907 foi avaliada quanto aos seguintes parâmetros fermentativos: temperatura, pH, suprimento de oxigênio ...
Schneider, Andrea Lima dos Santos
core
Sosialisasi Percepatan Program Kota Layak Anak (KLA) di Kecamatan Semarang Timur, Kota Semarang [PDF]
, 2013 SOSIALISASI PERCEPATAN PROGRAM KOTA LAYAK ANAK (KLA) DI KECAMATAN SEMARANG TIMUR, KOTA ...
Sudargo, S. (Sudargo) +8 more
core +1 more source
Implementasi Pembentukan Kabupaten Kota Layak Anak ( Kla ) Di Kabupaten Aceh Barat [PDF]
, 2023 Implementasi pembentukan Kota Layak Anak (KLA) merupakan pembangunan lingkungan perkotaan yang ramah anak sebagai upaya pengarusutamaan hak anak.
Sri Dwi Friwarti, Ratna Dewi
core +1 more source
Advanced Science, EarlyView.Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu +5 more
wiley +1 more source
Assessment of TWIST1 as an immunotherapeutic target of cancer [PDF]
, 2011 CD8+ T lymphocytes are key mediators of anti-tumour immunity, eliminating tumour cells through the recognition of tumour antigens. Increasing the number of characterised tumour antigens, especially those with highly specific tumour expression, may enable
Poon, E.C.C.
core
Comparison of methods for nitrous oxide emission estimation in full-scale activated sludge
Water Science and Technology, 2021 Nitrous oxide (N2O) gas transfer was studied in a full-scale process to correlate liquid phase N2O concentrations with gas phase N2O emissions and compare methods of determining the volumetric mass transfer coefficient, KLa.
Shanna Myers +4 more
doaj +1 more source
Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer
Advanced Science, EarlyView.Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian +11 more
wiley +1 more source
, 2023 The two major scale-up criteria in continuously stirred bioreactors are 1) constant aerated power input per volume (Pg/Vl), and 2) the volumetric O2 mass transfer coefficient (kla). However, Pg/Vl is only influenced by the stirrer geometry, stirrer speed,
Spadiut, Oliver +3 more
core +1 more source