This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li +6 more
wiley +1 more source
Under-diagnosed hypermucoviscous <i>Klebsiella pneumoniae</i> in Latin America: a hidden threat? single-center case series, Bogota, Colombia. [PDF]
Motta JC, Castillo JPL, Mendieta YM.
europepmc +1 more source
openaire +1 more source
ABSTRACT The World Health Organization and the U.S. Centre for Disease Control and Prevention have reported that antibiotic‐resistant infections with Pseudomonas aeruginosa present a significant health risk worldwide. In the genetic disease cystic fibrosis (CF), chronic antibiotic‐resistant Pseudomonas lung infections and persistent inflammation remain
Sharanya Sarkar +15 more
wiley +1 more source
Prevalence, clinical characteristics, and antibiotic resistance of carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital in Türkiye (2023-2025). [PDF]
Mermer S, Çağlayan E.
europepmc +1 more source
Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients
Chronic granulomatous disease is a rare inborn error of immunity characterized by the deficient production of reactive oxygen species in phagocytes, which are used in pathogen elimination. Affected individuals become susceptible to severe infections.
Leonardo Martinello da Rosa +4 more
wiley +1 more source
Genomic surveillance of multidrug-resistant Escherichia coli and Klebsiella in clinical and wastewater isolates from a paediatric hospital in Lima, Peru. [PDF]
Ayzanoa B +10 more
europepmc +1 more source
ABSTRACT Background Patients with acute myeloid leukemia (AML) undergoing induction chemotherapy are at high‐risk of bloodstream infections, including central line‐associated bloodstream infections (CLABSI) or mucosal barrier injury‐related infections (MBI‐LCBI).
Charles J. Weeks +16 more
wiley +1 more source
Epidemiological and characteristic differences of hypervirulent and classical <i>Klebsiella pneumoniae</i>: a clinical and genomic study in Southern China during the COVID-19 pandemic. [PDF]
Jiang Y +8 more
europepmc +1 more source
ABSTRACT Viral detection occurs frequently in critically ill patients. Patients with multiple viremic events had a higher ICU mortality. The highly sensitive mNGS technology has significantly enhanced viral pathogen detection rates. We enrolled 134 critically ill patients with severe infections who underwent mNGS testing during January 2019 to December
Yanting Sun +7 more
wiley +1 more source

