Results 71 to 80 of about 2,562 (158)

The revision of baphetids from the Middle Pennsylvanian of the Czech Republic: Morphology, ontogeny, palaeoecology, and the reassessment of the phylogeny of Baphetoidea

The Anatomical Record, EarlyView.
Abstract The baphetoids represent a clade of the Carboniferous stem‐tetrapods (Middle Mississippian—Middle Pennsylvanian) with a characteristic extension of the orbits into antorbital vacuities, which formed keyhole‐shaped openings on the skull. The more derived baphetids were crocodile‐like piscivores frequently occurring in coal‐bearing lacustrine ...
Pavel Barták, Martin Ivanov, Boris Ekrt
wiley   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Antibody engineering & therapeutics, the annual meeting of the antibody society December 7-10, 2015, San Diego, CA, USA [PDF]

, 2016
The 26th Antibody Engineering & Therapeutics meeting, the annual meeting of The Antibody Society united over 800 participants from all over the world in San Diego from 6-10 December 2015.
Bakker, J, Bradbury, AR, Carter, PJ, Lund-Johansen, F, Melis, JP, Pauthner, M, Reichert, JM, Ullman, C, Wurch, T, Yeung, J   +9 more
core   +1 more source

Confined Hot Carrier Cooling Via Excited‐State Energy Gap Engineering in Graphyne Carbon Allotropes

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The excited‐state energy gap (EEG), regulated by the concentration of sp‐hybridized carbon, provides an effective handle for tuning electron–phonon coupling behavior. This design enables long‐lived confinement of hot carriers near the top of the EEG with controllable energy levels.
Fulong Dai, Zhaozhao Xiong, Yingcong Liu, Feiyu Cheng, Haochun Sun, Zhenfa Zheng, Jin Zhao, Zhuojian Liang, Zhuo Kang, Yue Zhang   +9 more
wiley   +1 more source

Wafer‐Scale Deterministic Fabrication of Axis‐Ratio–Engineered Silicon Nanoparticles for On‐Resonance Electric–Magnetic Dipole Interference

Small, EarlyView.
Wafer‐scale top‐down fabrication yields silicon nanoparticles with exceptional uniformity (CV 1.7%–2.4%), enabling deterministic axis‐ratio tuning. At AR ≈$\approx$ 2.1, electric–magnetic dipoles overlap on‐resonance, producing near‐Kerker forward scattering (F/B ≈$\approx$ 12.5).
Taeyeong Kim, Jungchul Lee
wiley   +1 more source

Applying graph theory to protein structures:An atlas of coiled coils [PDF]

, 2018
Motivation: To understand protein structure, folding and function fully and to design proteins de novo reliably, we must learn from natural protein structures that have been characterised experimentally.
Ahnert, Alfonso Valencia, Andreeva, Andrew R Thomson, Berman, Bhattacharyya, Bosch, Boyken, Brinkmann, Chan, Cheng, Christopher W Wood, Crick, Derek N Woolfson, Dong, Fraga, Gail J Bartlett, Grigoryan, Grigoryan, Grindley, Hagberg, Harrison, Huang, Hulko, Jack W Heal, Joh, Kirchdoerfer, Kobler, Koronakis, Krissinel, Kuhlman, Liu, Liu, Lupas, Lupas, Mahendran, Malashkevich, Markosyan, Michalopoulos, Moutevelis, Niitsu, Parente, Parmeggiani, Rackham, Read, Sillitoe, Sim, Swain, Taylor, Taylor, Testa, Thomson, Walshaw, Walshaw, Walshaw, Wilson, Wood, Wood, Woolfson, Woolfson, Woolfson, Woolfson, Xiong, Zaccai   +63 more
core   +4 more sources

Extending the scope of coiled-coil crystal structure solution by AMPLE through improved ab initio modelling [PDF]

, 2020
The phase problem remains a major barrier to overcome in protein structure solution by X-ray crystallography. In recent years, new molecular-replacement approaches using ab initio models and ideal secondary-structure components have greatly contributed ...
Adams, Astbury, Astbury, Bibby, Blocquel, Bruhn, Caballero, Cohen, Cowtan, Crick, Crick, Crick, Das, Dauter, Davies, Dunce, Dunne, Dunne, Emsley, Forment, Guzenko, Guzenko, Hartmann, Hill, Keegan, Keegan, Keegan, Langer, Liebschner, Liu, Lupas, Lupas, McCoy, Moutevelis, Parry, Peng, Rodríguez, Rämisch, Rämisch, Sheldrick, Simons, Simons, Simons, Strelkov, Syrjanen, Thomas, Truebestein, Usón, Walshaw, Wood, Zhang   +50 more
core   +3 more sources

External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications

Small, EarlyView.
Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko, Jungsue Choi, Hyeonjeong Noh, Sohyeon Seo, Heedong Kwon, Seungjune Lee, Hyoyoung Lee   +6 more
wiley   +1 more source

Rapid Generation of Murine Bispecific Antibodies Using FAST-Ig^TM for Preclinical Screening of HER2/CD3 T-Cell Engagers

Antibodies
Bispecific antibodies (BsAbs) can bind to two different antigens, enabling therapeutic concepts that cannot be achieved with monoclonal antibodies. Immuno-competent mice are essential for validating drug discovery concepts, necessitating the development ...
Hikaru Koga, Haruka Kuroi, Rena Hirano, Hiroyuki Hirayama, Yoshiaki Nabuchi, Taichi Kuramochi   +5 more
doaj   +1 more source

Revised classification of glaciofluvial landforms in the Finnish sector of the Fennoscandian Ice Sheet

Boreas, EarlyView.
Effective and sustainable land use, conservation, and the use of geological resources (incl. raw materials, aggregates and groundwater) require a clear classification system of sedimentary units, with well‐defined vocabulary and unified mapping practices.
Jussi Hovikoski, Jukka‐Pekka Palmu, Tapio Väänänen, Markus Valkama, Antti E. K. Ojala, Satu Putkinen, Reijo Pitkäranta   +6 more
wiley   +1 more source