Results 31 to 40 of about 756,194 (303)
Applied Sciences, 2019 Engine knock has become the prime barrier to significantly improve power density and efficiency of the engines. To further look into the essence of the abnormal combustion, this work studies the working processes of normal combustion and knock combustion
Xi Wang +4 more
doaj +1 more source
Scientific Reports, 2021 CRISPR/Cas9-mediated homology-directed repair (HDR) is used for error-free targeted knock-in of foreign donor DNA. However, the low efficiency of HDR-mediated knock-in hinders establishment of knock-in clones.
Daisuke Arai, Yoichi Nakao
doaj +1 more source
Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration [PDF]
, 2018 Mutations in Cu/Zn superoxide dismutase 1 (SOD1) lead to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that disproportionately affects glutamatergic and cholinergic motor neurons.
Baskoylu, Saba N +10 more
core +3 more sources
Mutant loxP vectors for selectable marker recycle and conditional knock-outs [PDF]
, 2001 BACKGROUND: Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used as a model for gene knock-outs due to its high targeted integration
Arakawa, Hiroshi +2 more
core +3 more sources
Neutrino interactions with nuclei [PDF]
, 2009 We present a model for neutrino-nucleus scattering in the energy region relevant for present and forthcoming neutrino-oscillation experiments. The model is based on the RPA treatment of the nuclear responses in the quasi-elastic and Delta-resonance ...
Federico Sanchez +6 more
core +3 more sources
Prediction of lethal and synthetically lethal knock-outs in regulatory networks
, 2013 The complex interactions involved in regulation of a cell's function are captured by its interaction graph. More often than not, detailed knowledge about enhancing or suppressive regulatory influences and cooperative effects is lacking and merely the ...
A Inger +28 more
core +1 more source
, 2008 We analyze the two-player game of Knock 'em Down, asymptotically as the number of tokens to be knocked down becomes large. Optimal play requires mixed strategies with deviations of order sqrt(n) from the naive law-of-large numbers allocation.
Fill, James Allen, Wilson, David B.
core +1 more source
Molecular dynamics of nanodroplet impact: The effect of the projectile’s molecular mass on sputtering [PDF]
, 2016 The impact of electrosprayed nanodroplets on ceramics at several km/s alters the atomic order of the target, causing sputtering, surface amorphization and cratering.
Gamero Castano, M, Saiz Poyatos, F
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Kinetic modelling of runaway electron avalanches in tokamak plasmas
, 2015 Runaway electrons (REs) can be generated in tokamak plasmas if the accelerating force from the toroidal electric field exceeds the collisional drag force due to Coulomb collisions with the background plasma.
Decker, J. +5 more
core +1 more source