Results 51 to 60 of about 756,194 (303)

On the enhancement of nuclear reaction rates in high-temperature plasma [PDF]

, 2006
We argue that the Maxwellian approximation can essentially underestimate the rates of some nuclear reactions in hot plasma under conditions very close to thermal equilibrium.
Ballabio, Brandenburg, Chu, Cyburt, Fisher, Killeen, Kiptily, Korotkov, Källne, M. Nakamura, Mansfield, Mantsinen, Nakamura, Nakamura, Nakao, Nollett, Perkins, Rosenbluth, Schweinzer, V.T. Voronchev, Voronchev, Voronchev, Y. Nakao   +22 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Study on joint detection of fabricated concrete shear wall based on percussion method [PDF]

MATEC Web of Conferences, 2019
The knock detection method is one of the non-destructive testing methods for assembly prefabricated components. The knocker is used to knock on the concrete prefabricated components to be tested.
Song Bo, Li Jian, Wang Man sheng
doaj   +1 more source

Knock-Prediction System for Kerosene Engines Using In-Cylinder Pressure Signal

Energies, 2023
Piston engines fueled by kerosene have a strong application prospect in special vehicles and small aircrafts, but the low amount of octane in kerosene fuel causes its knock combustion phenomenon to be particularly serious.
Zhixin Xu, Guangzhou Cao, Minxiang Wei, Zhuowen Zhao, Zhiyu Xing, Yuzhang Ding   +5 more
doaj   +1 more source

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells. [PDF]

, 2017
In both multiple sclerosis and experimental autoimmune encephalomyelitis (EAE), the C-C chemokine receptor 6 (CCR6) is critical for pathogenic T helper 17 (Th17) cell migration to the central nervous system (CNS).
Atasoy, Ulus, Chen, Jing, Cramer, Carole, Drew, Paul D., Gorospe, Myriam, Martindale, Jennifer L., Yu, Shiguang   +6 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Analysis of Engine Knock Sensor

Communications, 2018
The paper deals with design of a simple device for the detection of this disorder. In the beginning of the paper the effect of the undesirable detonation combustion in internal combustion engines is described.
Daniel Korenciak, Miroslav Gutten, Juraj Adamec, Adam Glowacz, Adam Cichy   +4 more
doaj   +1 more source

Bayesian Non-Parametric Inference for Infectious Disease Data [PDF]

, 2014
We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed.
Knock, Edward S., Kypraios, Theodore
core  

Sequence-specific protein aggregation generates defined protein knockdowns in plants [PDF]

, 2016
Protein aggregation is determined by short (5-15 amino acids) aggregation-prone regions (APRs) of the polypeptide sequence that self-associate in a specific manner to form beta-structured inclusions.
Aesaert, Stijn, Betti, Camilla, Coutuer, Silvie, De Rycke, Riet, De Smet, Frederik, Gallardo, Rodrigo, Inzé, Dirk, Mishev, Kiril, Rombaut, Debbie, Rousseau, Frederic, Russinova, Eugenia, Schymkowitz, Joost, Van Breusegem, Frank, Van Lijsebettens, Maria, Vanhoutte, Isabelle, Vuylsteke, Marnik, Xu, Jie   +16 more
core   +2 more sources