Results 141 to 150 of about 2,060,910 (365)

Interaction of Tau, IL-6 and mitochondria on synapse and cognition following sevoflurane anesthesia in young mice

open access: yesBrain, Behavior, & Immunity - Health, 2020
Tau phosphorylation is associated with cognitive impairment in young mice. However, the underlying mechanism and targeted interventions remain mostly unknown.
Jie Zhang   +7 more
doaj  

Effect of Predators of Juvenile Rodents on the Spread of the Hantavirus Epidemic [PDF]

open access: yesarXiv, 2005
Effects of predators of juvenile mice on the spread of the Hantavirus are analyzed in the context of a recently proposed model. Two critical values of the predation probability are identified. When the smaller of them is exceeded, the hantavirus infection vanishes without extinguishing the mice population.
arxiv  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Progress of the MICE experiment [PDF]

open access: yesarXiv, 2015
The international Muon Ionization Cooling Experiment (MICE) will perform a systematic investigation of ionization cooling of a muon beam. The demonstration is based on a simplified version of a neutrino factory cooling channel. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation has been ...
arxiv  

Pituitary and Testicular Function in Growth Hormone Receptor Gene Knockout Mice * [PDF]

open access: bronze, 1999
Varadaraj Chandrashekar   +3 more
openalex   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Diminished Immune Response and Elevated Abundance in Gut Microbe Dubosiella in Mouse Models of Chronic Colitis with GBP5 Deficiency

open access: yesBiomolecules
Guanylate binding protein 5 (GBP5) is an emerging immune component that has been increasingly recognized for its involvement in autoimmune diseases, particularly inflammatory bowel disease (IBD).
Yichen Li   +5 more
doaj   +1 more source

Antagonism of the Thromboxane‐Prostanoid Receptor as a Potential Therapy for Cardiomyopathy of Muscular Dystrophy

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Muscular dystrophy (MD) causes a progressive cardiomyopathy characterized by diffuse fibrosis, arrhythmia, heart failure, and early death. Activation of the thromboxane‐prostanoid receptor (TPr) increases calcium transients in cardiomyocytes ...
James D. West   +10 more
doaj   +1 more source

Determination of a dineutron correlation in Borromean nuclei via a quasi-free knockout ($p,pn$) reaction? [PDF]

open access: yesarXiv, 2016
To discuss the dineutron correlation in the ground state, the quasi-free neutron knockout reaction on $^6$He is investigated.In the present work, the momentum distribution of the two emitted neutrons is calculated with the $\alpha$~+~$n$~+~$n$ three-body model and a simple reaction model to assess the effects of the knockout process via the $^5$He ...
arxiv  

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