Results 161 to 170 of about 2,060,910 (365)

Reaction mechanism of quasi-free knockout processes in exotic RI beam era [PDF]

arXiv
The quasi-free nucleon knockout reaction has been revealed the single-particle nature of nuclei. Thanks to the advances in experimental techniques and reaction theory, various new aspects of nuclei are being revealed by knockout reactions. In this article, we review the basic concept of the quasi-free knockout reaction, and recent achievements in the ...
arxiv  

Chronic regulation of arterial blood pressure in ANP transgenic and knockout mice: Role of cardiovascular sympathetic tone [PDF]

, 1999
Luis G. Melo
openalex   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source

ApoA-II maintains HDL levels in part by inhibition of hepatic lipase: studies in apoA-II and hepatic lipase double knockout mice

Journal of Lipid Research, 1999
High density lipoprotein (HDL) cholesterol levels are inversely related to the risk of developing coronary heart disease. Apolipoprotein (apo) A-II is the second most abundant HDL apolipoprotein and apoA-II knockout mice show a 70% reduction in HDL ...
Wei Weng, Neal A. Brandenburg, Shaobin Zhong, Joanna Halkias, Lin Wu, Xian-cheng Jiang, Alan Tall, Jan L. Breslow   +7 more
doaj  

Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb β ^s -globin yeast artificial chromosome: A mouse model of sickle cell anemia [PDF]

, 1998
Judy C. Chang, Ronghua Lu, Chin Jia Lin, Shan-Mei Xu, Yuet Wai Kan, Susanna Porcu, Elaine J. Carlson, Michael Kitamura, Suya Yang, Linda Flebbe-Rehwaldt, Karin Gaensler   +10 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Macroorchidism in FMR1 Knockout Mice Is Caused by Increased Sertoli Cell Proliferation during Testicular Development [PDF]

, 1998
K. E. Slegtenhorst-Eegdeman
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Poly(ADP-ribose) polymerase activity is not affected in ataxia telangiectasia cells and knockout mice [PDF]

, 1999
Françoise Dantzer, Josiane Ménissier‐de Murcia, Carrolee Barlow, Anthony Wynshaw‐Boris, Gilbert de Murcia   +4 more
openalex   +1 more source

Suppression of Intestinal Polyposis in Apc Δ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Cell, 1996
M. Oshima, J. Dinchuk, S. Kargman, H. Oshima, Bruno C. Hancock, E. Kwong, J. Trzăskos, Jilly F. Evans, M. Taketo   +8 more
semanticscholar   +1 more source