Results 271 to 280 of about 777,239 (352)

Rescue of <i>Iqsec2</i> Knockout Mice with Human IQSEC2 Adeno-Associated Virus Mediated Gene Therapy. [PDF]

Int J Mol Sci
Soundararajan D, Kouyama-Suzuki E, Shirai Y, Orth S, Borisov V, Israel Y, Weiss Y, Avi-Isaac L, Garoma NH, Lache O, Levy NS, Li S, Zang W, Netser S, Wagner S, Jimenez G, Frankel WN, Tabuchi K, Sands TT, Levy AP.   +19 more
europepmc   +1 more source

The Role of Flotillins in Regulating Aβ Production, Investigated Using Flotillin 1-/-, Flotillin 2-/- Double Knockout Mice

, 2014
Vassilis Bitsikas, Kirsi Riento, Jonathan D. Howe, Nicholas P. Barry, Benjamin J. Nichols   +4 more
openalex   +2 more sources

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Intrahippocampally Injected Human Recombinant Clusterin Reduces Amyloid-β Aggregate Size in Cerebral Arteriole Walls of Clusterin Knockout Mice. [PDF]

Neuropathol Appl Neurobiol
Laslo A, Boghițoiu TG, Chinezu L, Manu D, Dumitru Ivanescu A, Cordoș BA, Wilson MR, Banescu C, Fryer JD, Verma A, Dewing JM, Carare RO.   +11 more
europepmc   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

Advanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr, Saptarshi Biswas, Jacob Aragon, Asaf Dana, Jasmine Sureka, Vaaridhi Ramanuja, Jeevika Thazhaiselvam, Sarah E. Miller, Taylor H. Ware, Akhilesh K. Gaharwar   +9 more
wiley   +1 more source

PAC1 Receptor Knockout Mice Reveal Critical Links Between ER Stress, Myelin Homeostasis, and Neurodegeneration. [PDF]

Int J Mol Sci
Withana M, Bradfield L, Jansen MI, Musumeci G, Waschek JA, Castorina A.   +5 more
europepmc   +1 more source

NR4A1 (Nur77) Mediates Thyrotropin-Releasing Hormone-Induced Stimulation of Transcription of the Thyrotropin β Gene: Analysis of TRH Knockout Mice

, 2012
Yasuyo Nakajima, Masanobu Yamada, Ryo Taguchi, Nobuyuki Shibusawa, Atsushi Ozawa, Takuya Tomaru, Koshi Hashimoto, Tsugumichi Saito, Takafumi Tsuchiya, Shuichi Okada, Tetsurou Satoh, Masatomo Mori   +11 more
openalex   +2 more sources

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

Advanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou, Jiongyi Yan, Dick F. Firdaus, Amy Jin, Jiaxuan Li, Shushan Wang, Ran Chen, Xudong Tao, Zehao Ji, Yi Liu, Zichen Wang, Christos Margadji, Mark Kotter, J. Axel Zeitler, George G. Malliaras, Ronan Daly, Andrew Gleadall, Sebastian W. Pattinson   +17 more
wiley   +1 more source

Gene Expression Profiling in the Cortex of Fabp4 Knockout Mice. [PDF]

Neuropsychopharmacol Rep
Kirikae H, He X, Ohnishi T, Miyazaki H, Yoshikawa T, Owada Y, Maekawa M.   +6 more
europepmc   +1 more source

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

Advanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li, Yifan Pan, Chikahiro Imashiro, Chaolun Xu, Jianxian He, Jingao Xu, Kewei Song, Ze Zhang, Chen Gao, Junbo Jiang, Runhuai Yang, Kayo Hirose, Shinjiro Umezu   +12 more
wiley   +1 more source