Results 71 to 80 of about 2,309,755 (329)

Screening for depression in children and adolescents in primary care or non-mental health settings: a systematic review update

open access: yesSystematic Reviews
Background The transition from childhood to adolescence is associated with an increase in rates of some psychiatric disorders, including major depressive disorder, a debilitating mood disorder.
Andrew Beck   +17 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Performing Hybrid Recommendation in Intermodal Transportation – the FTMarket System’s Recommendation Module [PDF]

open access: yes, 2009
Diverse recommendation techniques have been already proposed and encapsulated into several e-business applications, aiming to perform a more accurate evaluation of the existing information and accordingly augment the assistance provided to the users ...
Lazanas, Alexis
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Knowledge synthesis research: a bibliometric analysis

open access: yesJournal of Clinical Epidemiology, 2016
The purpose of this article is to describe the volume and attributes of original research available in PubMed on emerging knowledge synthesis methods (excluding traditional systematic reviews) published by researchers.Bibliometric analysis.Six-hundred eight studies related to the topic of knowledge synthesis methods were analyzed.
Perrier, Laure   +4 more
openaire   +3 more sources

AutoBayes: A System for Generating Data Analysis Programs from Statistical Models

open access: yes, 2003
Data analysis is an important scientific task which is required whenever information needs to be extracted from raw data. Statistical approaches to data analysis, which use methods from probability theory and numerical analysis, are well-founded but ...
Fischer, Bernd, Schumann, Johann
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Outcomes and Characteristics of Interdisciplinary Self-Management Interventions for Older Adults Living with Chronic Pain: Insights from a Scoping Review

open access: yesJournal of Ageing and Longevity
Introduction: Up to 50% of community-dwelling older adults report living with some chronic pain that interferes with their daily functioning and leads to disabilities.
Samuel Turcotte   +13 more
doaj   +1 more source

Plan Synthesis for Knowledge and Action Bases [PDF]

open access: yes, 2016
We study plan synthesis for a variant of Knowledge and Action Bases (KABs), a rich, dynamic framework, where states are description logic (DL) knowledge bases (KBs) whose extensional part is manipulated by actions that possibly introduce new objects from
Calvanese, Diego   +3 more
core  

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