Results 91 to 100 of about 24,464,352 (186)

Superposition of complexes of KPC-2 and SHV-1 bound with avibactam.

, 2015
Superimposed are KPC-2 (cyan carbon atoms) and SHV-1 (grey carbon atoms). The nitrogen N1 is labelled ‘1’ and ‘1’” for KPC-2 and SHV-1, respectively, to indicate the differences in the chirality and direction of the lone pair electrons that nitrogen in ...
Nikhil P. Krishnan (792291), Focco van den Akker (158508), Nhu Q. Nguyen (792292), Robert A. Bonomo (188763), Krisztina M. Papp-Wallace (792293)   +4 more
core   +1 more source

New Insights in bla_KPC Gene Mobilization in Pseudomonas aeruginosa: Acquisition of bla_KPC-3 and Identification of a New Tn2-like NTE Mobilizing bla_KPC-2

Antibiotics
Carbapenem-resistant Pseudomonas aeruginosa is a major cause of healthcare associated infections in hospitalized patients and what is more warring with reduced therapeutic options.
Deisy Abril, Juan Bravo-Ojeda, Julio-Cesar Garcia, Aura Lucia Leal-Castro, Carlos Humberto Saavedra-Trujillo, Johana Madroñero, Rosa-Helena Bustos, Ricaurte Alejandro Marquez-Ortiz, Zayda Lorena Corredor Rozo, Natasha Vanegas Gómez, Javier Escobar-Pérez   +10 more
doaj   +1 more source

New Small Plasmid Harboring bla(KPC-2) in Pseudomonas aeruginosa

, 2016
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Processo FAPESP: 2014/14494-8The aim of this study was to characterize the genetic context of bla(KPC-2) in Pseudomonas aeruginosa sequence type 244 from Brazil.
Chandler, Michael, Varani, Alessandro de Mello, Costa Darini, Ana Lucia, Galetti, Renata, Andrade, Leonardo Neves, Varani, Alessandro de Mello [UNESP]   +5 more
core   +1 more source

Evaluation of the Bruker MALDI Biotyper (MBT) subtyping module for detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacterales in a Canadian clinical microbiology laboratory

Microbiology Spectrum
Early detection of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacterales enables prompt initiation of appropriate antimicrobial therapy and infection prevention and control measures.
Emma Finlayson-Trick, Heather Glassman, Jasmine Ahmed-Bentley, Xinhe Liu, Linda Tsui, Lori Sung, Charlene Porter, Claudine Desruisseaux, Valery Lavergne, Suefay Liu, Jennifer Tat, Anthony Lieu, Aruna Uma Chandran, Marthe K. Charles   +13 more
doaj   +1 more source

CHROMagar KPC. Comparación con el método propuesto por los Centros para el Control y Prevención de Enfermedades (CDC, EE.UU.) para el estudio de portación rectal y evaluación de falsos positivos CHROMagar KPC. Comparison with the method proposed by the Centers for Disease Control and Prevention (CDC, USA) for rectal screening and evaluation of false positive results

Revista Argentina de Microbiología, 2012
Se cultivaron 81 hisopados rectales en el medio CHROMagar KPC y por el método del CDC. Fueron positivos para Klebsiella pneumoniae KPC en CHROMagar KPC, 9/81 y 6/81 con el método del CDC. El medio CHROMagar KPC tuvo dos falsos positivos: 1 K.
Laura Errecalde, Sandra Cogut, Mariana Erbín, Liliana Jordá Vargas, Eugenia Cattani, Tamara Posse, Silvia Tutzer, Ricardo Hermes, Sara Kaufman   +8 more
doaj  

Real-world use of imipenem/cilastatin/relebactam for the treatment of KPC-producing Klebsiella pneumoniae complex and difficult-to-treat resistance (DTR) Pseudomonas aeruginosa infections: a single-center preliminary experience

Frontiers in Microbiology
IntroductionReal-life experience with imipenem/cilastatin/relebactam (IMI/REL) for the treatment of KPC-producing Klebsiella pneumoniae complex (KPC-Kp) and difficult-to-treat resistance (DTR) Pseudomonas aeruginosa (DTR-PA) infections is herein ...
Cristiana Leanza, Maria Teresa Mascellino, Lorenzo Volpicelli, Sara Covino, Antonio Falletta, Francesca Cancelli, Cristiana Franchi, Martina Carnevalini, Claudio M. Mastroianni, Claudio M. Mastroianni, Alessandra Oliva   +10 more
doaj   +1 more source

Phenyl boronic acids development led to validated leads active in clinical strains overexpressing KPC-2: a step against bacterial resistance.

, 2018
The emergence and dissemination of multi drug resistant (MDR) pathogens resistant to near all available antibiotics poses a significant threat in clinical therapy. Among them, Klebsiella pneumoniae clinical isolates overexpressing KPC-2 carbapenemase are
Linciano, Pasquale, Perilli, Mariagrazia, Linciano Pasquale, Celenza, Giuseppe, Giuseppe Celenza, Blazquez, Jesús, Jesús Blazquez, Perilli Mariagrazia, Cendron, Laura, Bellio, Pierangelo, Oliver Antonio, Oliver, Antonio, Mattia Vicario, Blazquez Jesús, Celenza Giuseppe, Antonio Oliver, Tondi Donatella., Tondi, Donatella, Pasquale Linciano, Bellio Pierangelo, Laura Cendron, Pierangelo Bellio, Mariagrazia Perilli, Donatella Tondi, Vicario Mattia, Vicario, Mattia, Cendron Laura   +26 more
core   +1 more source

Minimum Evolution tree of amino acid sequences for KPC-2 to KPC-17.

, 2014
KPC-15 carbapenemase was our newly discovered and appeared to be homogenous with KPC-4 closely. The amino acid sequences of KPCs based on the data of Figure 1. This comparison was designed and analysed using MEGA 5.05 software.
Linjun Yang (652707), Dongguo Wang (652706), Jiayu Chen (106469), Yonghua Mou (652708), Yijun Yang (187046)   +4 more
core   +1 more source

First isolation of Salmonella Javiana with KPC-2 in Paraguay [PDF]

Revista de salud publica del Paraguay, 2017
Nancy Melgarejo-T, Mario Martinez, Rossana Franco, Miryan Falcón, Mercedes Álvarez, Helena Ortiz, Juan Irala   +6 more
openaire   +1 more source

Predominant transmission of KPC-2 carbapenemase in Germany by a unique IncN plasmid variant harboring a novel non-transposable element (NTE KPC -Y) [PDF]

Carbapenemase-producing Enterobacterales (CPE) pose a major public health threat. Despite active infection prevention efforts, the incidence of KPC-2 carbapenemase-producing Enterobacterales (KPC2-CPE) continues to increase worldwide.
Falgenhauer, Linda, Imirzalioglu, Can, Chakraborty, Trinad, Rezazadeh, Yalda, Falgenhauer, Jane, Yao, Yancheng   +5 more
core   +1 more source