Results 101 to 110 of about 24,464,352 (186)

Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

Annals of Clinical Microbiology and Antimicrobials
Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing bla KPC and bla NDM poses a serious threat to public health.
Qian Wang, Yue Liu, Ran Chen, Meng Zhang, Zaifeng Si, Yueling Wang, Yan Jin, Yuanyuan Bai, Zhen Song, Xinglun Lu, Mingju Hao, Yingying Hao   +11 more
doaj   +1 more source

sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.

PLoS Pathogens
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) has significant challenges to human health and clinical treatment, with KPC-2-producing CRKP being the predominant epidemic strain.
Yibo Bai, Chonghong Xie, Yue Zhang, Zhijie Zhang, Jianhua Liu, Guixue Cheng, Yan Li, Di Wang, Bing Cui, Yong Liu, Xiaosong Qin   +10 more
doaj   +1 more source

Comparative analysis of KPC-2-encoding chimera plasmids with multi-replicon IncR:IncpA1763-KPC:IncN1 or IncFIIpHN7A8:IncpA1763-KPC: IncN1

Infection and Drug Resistance, 2019
Daofeng Qu,1,2 Yang Shen,2 Lingfei Hu,1 Xiaoyuan Jiang,1 Zhe Yin,1 Bo Gao,1 Yuee Zhao,1 Wenhui Yang,1 Huiying Yang,1 Jianzhong Han,2 Dongsheng Zhou1 1State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology ...
Qu D, Shen Y, Hu L, Jiang X, Yin Z, Gao B, Zhao Y, Yang W, Yang H, Han J, Zhou D   +10 more
doaj  

Decadal Evolution of KPC-related plasmids in Pseudomonas aeruginosa high-risk clone ST463 in Zhejiang, China

Communications Biology
Klebsiella pneumoniae carbapenemase-producing Pseudomonas aeruginosa (KPC-PA) isolates have quickly expanded in China, especially the high-risk clone ST463. We aimed to explore the evolution of KPC-related plasmids driving ST463 clone success.
Yue Li, Qing Yang, Minhua Chen, Heng Cai, Li Fang, Junxin Zhou, Rui Weng, Hanming Ni, Yan Jiang, Xiaoting Hua, Yunsong Yu   +10 more
doaj   +1 more source

Boronic acid inhibitors of the class A beta-lactamase KPC-2

, 2018
The rapid rise of antimicrobial resistance is one of the greatest challenges currently facing medical science. The most common cause of resistance to β-lactam antibiotics is the expression of β-lactamase enzymes, such as KPC-2. As such the development of
Zhou, J, Stapleton, P, Haider, S, Healy, J   +3 more
openaire   +2 more sources

Occurrence of KPC-2-producing Klebsiella pneumoniae strains in hospital wastewater [PDF]

Journal of Hospital Infection, 2011
Chagas, T.P.G., Seki, L.M., da Silva, D.M., Asensi, M.D.   +3 more
openaire   +2 more sources

KPC-157 and KPC-181 carbapenemases produced by Citrobacter freundii ST522 and Klebsiella pneumoniae ST258 isolated from wastewater

Background While novel KPC variants continue to emerge among clinically relevant Enterobacterales from hospital settings, their occurrence in impacted aquatic environments has been poorly investigated.
Lincopan, Nilton, Power, Pablo, Brunetti, Florencia Lourdes, Bueno, Giovanna Carrasco, Schenkman, Sergio, Furlan, João Pedro Rueda, Silva, Renan Lourenço Oliveira, Sato, Maria Ines Zanoli, Sousa Carmo, Rubens Renato, Barbosa, Mikaela Renata Funada   +9 more
core   +1 more source

Repeated insertions at positions 261-280 in KPC-2 highlight a ceftazidime-avibactam resistance hotspot. [PDF]

iScience
Li Y, Salman S, Liu R, Wang K, Gong L, Sun T, Xu H.   +6 more
europepmc   +1 more source

Molecular Epidemiology of KPC-2 Producing Klebsiella pneumoniae [PDF]

SOJ Microbiology & Infectious Diseases, 2017
openaire   +1 more source

Genomic characterization of carbapenemase-producing Enterobacterales from wastewater reveals the convergence of KPC-2 and GES-16 in Brazil. [PDF]

Environ Monit Assess
Furlan JPR, Bueno GC, Sousa-Carmo RR, Silva RLO, Barbosa MRF, Sato MIZ, Lincopan N, Schenkman S.   +7 more
europepmc   +1 more source