Results 111 to 120 of about 85,174 (277)
Protein Science, Volume 35, Issue 7, July 2026.Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone +15 more
wiley +1 more source
Nuclear kpc-sized Disks of Spiral Galaxies [PDF]
Symposium - International Astronomical Union, 1999 The complex structure of nuclear disks of normal spiral galaxies is illustrated with the example of five galaxies, observed at the 6m telescope. The problem of gravitational stability of nuclear disks is briefly discussed.
Zasov, A. V., Moiseev, A. V.
openaire +2 more sources
Jurnal Transformative, 2017 This paper discusses about political process of alienation by bureaucrat in Central Lombok region. Political policy of alienation is conducted by government in purpose to punish several bureaucrats that politically oppose in local election.
Dedi Zulkarnain Pratama
doaj +3 more sources
Infection and Drug Resistance, 2020 Haidi Karam-Allah Ramadan,1 Manal A Mahmoud,2 Mohamed Zakaria Aburahma,1 Amal A Elkhawaga,3 Mohamed A El-Mokhtar,3 Ibrahim M Sayed,3,4 Amal Hosni,5 Sahar M Hassany,1 Mohammed A Medhat1 1Department of Tropical Medicine and Gastroenterology, Faculty of ...
Ramadan HKA +8 more
doaj
Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Ceftazidime-avibactam use for KPC-Kp infections: a retrospective observational multicenter study.
Clinical Infectious Diseases, 2021 semanticscholar +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, Volume 13, Issue 35, 24 June 2026.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Tumorigenicity of KC and KPC cell lines.
, 2013 (A) The tumorigenic properties of UN-KC-6141, UN-KPC-960, and UN-KPC-961 cells were evaluated after orthotopic (OT) (N = 7) implantation of 1×106 cells in the respective mice background. Subcutaneous (SC) injections of UN-KPC-961 cells (5×106 cells) were
Kavita Mallya (230388) +5 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, Volume 13, Issue 35, 24 June 2026.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Interstrand crosslinking agents inhibit Palb2-KPC and Brca2-KPC tumor growth in vivo.
, 2019 (A, B) Growth curves of allograft tumors in nude mouse models. MMC and Cisplatin treatment inhibited growth of Palb2-KPC, Brca1-KPC and Brca2-KPC tumors (Means ± SEM; ***Pvs vehicle treated group using).
Dongju Park (8190660) +8 more
core +1 more source