Results 101 to 110 of about 57,276 (230)

Interstrand crosslinking agents inhibit Palb2-KPC and Brca2-KPC tumor growth in vivo.

open access: yes, 2019
(A, B) Growth curves of allograft tumors in nude mouse models. MMC and Cisplatin treatment inhibited growth of Palb2-KPC, Brca1-KPC and Brca2-KPC tumors (Means ± SEM; ***Pvs vehicle treated group using).
Dongju Park (8190660)   +8 more
core   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang   +11 more
wiley   +1 more source

Tumorigenicity of KC and KPC cell lines.

open access: yes, 2013
(A) The tumorigenic properties of UN-KC-6141, UN-KPC-960, and UN-KPC-961 cells were evaluated after orthotopic (OT) (N = 7) implantation of 1×106 cells in the respective mice background. Subcutaneous (SC) injections of UN-KPC-961 cells (5×106 cells) were
Kavita Mallya (230388)   +5 more
core   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3214-3222, September 2026.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang   +4 more
wiley   +1 more source

High prevalence of KPC-2-producing hypervirulent Klebsiella pneumoniae causing meningitis in Eastern China

open access: yes, 2019
Min Xu,1,* Yiqi Fu,2,* Yunhui Fang,3 Hao Xu,3 Haishen Kong,3 Yanchao Liu,1 Yu Chen,1,3 Lanjuan Li3 1Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Center of Clinical Laboratory, The First Affiliated Hospital, College of ...
Fang Y   +7 more
core  

Invariant Subspaces on KPC-Hypergroups

open access: yesZurnal matematiceskoj fiziki, analiza, geometrii, 2019
In this paper, we study translation invariant function spaces and spectral analysis on KPC-hypergroups and describe a correspondence between ideals in the algebra of compactly supported measures and varieties of continuous functions on a KPC-hypergroup. L?szl? Szkelyhidi and Seyyed Mohammad Tabatabaie, 2019.
Szkelyhidi, L?szl?   +1 more
openaire   +1 more source

A Clinically Aligned Two‐Stage Machine Learning Framework for Predicting Hungry Bone Syndrome After Parathyroidectomy

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin   +10 more
wiley   +1 more source

Investigation of the Mechanism of Total Flavonoids From Chuju in Mitigating Cerebral Ischemia–Reperfusion Injury in Rats Using Untargeted Metabolomics

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
Total flavonoids of Chuju (TFCJ) protect against cerebral ischemia–reperfusion injury (CIRI) in rats by reducing infarct volume, alleviating oxidative stress, and regulating metabolic pathways including the TCA cycle, glycolysis, pentose phosphate pathway (PPP), and aspartate–glutamate metabolism.
Guanglei Zhang   +7 more
wiley   +1 more source

Genomic characterization of novel IncFII-type multidrug resistant plasmids p0716-KPC and p12181-KPC from Klebsiella pneumoniae

open access: yes, 2017
This study aimed to genetically characterize two fully-sequenced novel IncFII-type multidrug resistant (MDR) plasmids, p0716-KPC and p12181-KPC, recovered from two different clinical Klebsiella pneumoniae isolates.
Hui Wang   +13 more
core   +1 more source

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